Nursing education in Europe has been built by guidelines of the European Higher Education Area (EHEA) and European Union (EU) (EHEA, 2010; EU, 2005). The main goal is to increase staff and students' mobility and to facilitate employability. Higher education can no longer take place in the traditional way of sitting in a classroom. Nor can prospective students afford of taking time off from work to undertake a period of study. Flexible learning options, including part time study, accelerated programs, bridge programs and work based learning, blended programs are needed to ensure that nursing education is offered and delivered in the most cost-effective and time-efficient way. Therefore, these aspects have to be built into the programs through the delivery of educational technologies such as e-Learning, distance learning and virtual simulation. The growing importance of technology in health care calls for interdisciplinary study programs in which students with various backgrounds work together in exploring and designing new solutions for real-life problems. E-learning technologies have been explored extensively for students of health professionals in an academic context. This terminology involves a variety of electronic, digital or mobile devices used to support learning. E-learning has many advantages: it reduces time, it is flexible and accessible, it can be profitable and it allows students to learn at their own pace and from the place they choose. In addition, e-learning can present a variety of multimedia components such as text, audio, still images and moving images to support the acquisition of knowledge and skills. Results of systematic reviews support that this is an effective alternative way to learn . Some reviews on e-learning used by nurses or nursing students has positive impacts, especially knowledge, level of self-efficacy, attitudes, barriers and facilitators, skills and satisfaction regarding the use of e-learning .For this reason, it is necessary to work on the development of tools that facilitate student e-learning and that are integrated efficiently within the training and educational programs.For all the above, the general aim of the project “Digital Toolbox for innovation in nursing education (I-BOX)” is to design and develop audiovisual materials in open-access format related to procedures and nursing techniques in a simulation environment that will help graduate nursing students to improve their education and training. All this materials will be shared on a digital and collaborative tool that will allow restructuring content in m-learning format. This project will be developed by five higher education institutions from Spain, Slovenia, Russia, Finland and Austria that offers nursing programs working together in a Strategic Partnership. This Strategic Partnership will create a network of universities involved in developing new materials in nursing education, to achieve the following specific goals and related activities:•To develop educational and audiovisuals e-learning material (videos, postcasts..) following ASSURE model related to procedures and nursing techniques in a simulation environment. ASSURE is an instructional design model that has the goal of producing more effective teaching and learning.•To validate and adapt to cultural context the DREEM tool to Spanish and Russian language. The Dundee Ready Education Environment Measure (DREEM) was published in 1997 as a tool to evaluate educational environments of medical schools and other health training settings.•To develop a virtual space (on line platform) in web format where students and teachers can share the material and information in open access (scientific articles, tools, infographics, news, etc.). In this platform will be a space for virtual debate where students and teachers from different countries can share doubts and raise real situations to solve collaboratively. •To develop recommendations of best practices to implement educational e-learning material within the Nursing Education (theoretical or practical subject). The fact that these audiovisual materials are open-access enables students, teachers and also health professionals to keep updated on the techniques, share knowledge without borders and therefore ease generation of new expertise. It also aims to be a reference tool for all kind of educational organizations and professional individuals that enables to spread knowledge at all levels.The objectives of the I-BOX project are aligned with the horizontal strategy of open education and innovative practices in a digital era, because promotes innovative methods and pedagogies and develops digital learning materials and tools open-access.