Global Health (GH) is a vital discipline, generating knowledge on current and emerging GH issues, promoting international collaborations, and setting a framework for understanding of how countries can collectively respond to GH challenges. However, due to a lack of internal resources and/or limited access to external funding, GH has not been established as a discipline within middle-income countries of Eastern Europe/Central Asia (EECA). This lack of GH capacity poses health risks to these countries’ populations and globally.The project’s over-arching aim is to enable 3 EECA coountries – Georgia, Ukraine and Kazakhstan – to build capacity and integrate GH into academic programmes. This will be achieved through development of technical knowledge in priority GH topics and GH-relevant research methods, capacity building of academic staff in pedagogical and methodological approaches to designing/delivering new curricula, jointly developing GH courses, and the forging/reinforcement of collaborations between HEIs and non-academic organisations in Partner and Programme countries. Curricula for 6 new GH thematic courses and 3 GH research methods courses will be produced in English, Russian, Georgian, Ukrainian and Kazakh. These courses will be integrated into Partner HEIs’ existing masters and PhDs and delivered to 25 – 165 students in year 1 of implementation. In addition, Partner HEIs will be supported to develop and deliver an intensive EECA Regional GH Academy course for staff and public health practitioners. A EECA Regional Alliance for GH will be established to serve as an inter-institutional and inter-sectoral mechanism for collaboration, knowledge exchange, training and research on priority GH issues. The project will develop a strong platform of GH knowledge and expertise in EECA and ensure mechanisms are in place for the discipline to grow. Staff and students will be equipped with knowledge and skills needed to meaningfully enhance international cooperation.