GI-NI aims to contribute to an inclusive Europe of shared prosperity, by providing a better understanding of the changes and joint impact of three major transformations: technological progress, globalisation and migration; and offering policy and governance solutions to better equip citizens and companies, securing more equal opportunities and outcomes. We use a multidisciplinary research approach by a top-tier consortium with international stakeholder engagement throughout the project. GI-NI has five objectives: 1. Measure impacts of the three transformations on work, skills, and inequality; 2. Synthesize and analyse their interaction; 3. Foster dialogue and co-create future options with stakeholders; 4. Collect and consolidate data and produce future projections; 5. Identify policy and governance options for inclusion and equality. GI-NI generates this by: building on state-of-the-art research and other EU projects; using innovative methods; combining EU-wide and international micro- and macro-data; addressing gaps in knowledge and insights on data, joint impacts, and futures. We generate three new outcomes: 1. New scientific understanding of joint impacts of transformations; 2. Multilateral policy solutions; 3. New evidence in support of a robust EU policy strategy. GI-NI carefully disseminates and valorises results. GI-NI addresses the general priorities of the H2020 Work Programme ‘Europe in a changing world’: 1. Address concerns of EU citizens on migration and the 4th Industrial Revolution by better understanding their impact on work, skills and equality and presenting scenarios and solutions; 2.Collaborate with international partners beyond EU borders (China, India, Brazil, Singapore); 3.Contribute to sustainable prosperity by bottom-up firm-level evidence and solutions; 4.Contribute to UN’s Sustainable Development Goals 1, 5, 8, 9, 10 and 17. In conclusion, we provide insights and solutions to anticipate change for more equality in work and skills.