CHANSE, Collaboration of Humanities and Social Sciences in Europe, is a joint initiative of 27 research funding organisations from 24 countries. The CHANSE Programme builds on the experience of two existing networks: HERA (Humanities in the European Research Area) and NORFACE (New Opportunities for Research Funding Agency Cooperation in Europe) supporting research in humanities and social sciences respectively. The main goal of the CHANSE inititive is to launch a transnational call for collaborative projects focused on the topic of Transformations: Social and cultural dynamics in the digital age. The objective of this call will be to help understand how digital innovations give rise to social and cultural changes, and are also influenced by society and culture. The joint research call combines the analytic and transformative powers of the humanities and social sciences in understanding processes of change and considering solutions when societies face the introduction of innovations. With a budget of over EUR 36 million, including expected EC co-funding, CHANSE consortium plans to fund excellent research projects conducted by research teams from at least three countries involved in the Programme. CHANSE will strive to produce a lasting effect on the research landscape by cultivating durable research collaboration across multiple national and regional borders, disciplinary boundaries, and stakeholders, thus supporting the sharing of excellence and promoting widening participation in the European Research Area. CHANSE will also strongly support knowledge exchange activities and foster relationships between academia and relevant stakeholders, as well as explore and develop new joint actions. By offering new opportunities for international research cooperation in a critical area of enquiry, the CHANSE Programme will deliver a broad range of academic, societal and economic impacts within, across and beyond the partner countries.