The Bio Innovation of a Circular Economy for Plastics (BioICEP) is a pan European-Chinese collaboration formed to reduce the burden of plastic waste in the environment. Different mixed plastic pollution environments are represented, with specific partners selected which have the expertise and facilities to carry out the necessary technical innovations. A number of innovative booster technologies are at the core of this solution accentuating, expediting, and augmenting mixed plastics degradation to levels far in excess of those current achievable. Our approach is The Bio Innovation of a Circular Economy for Plastics (BioICEP) consortium is a pan European-Chinese collaborative formed to reduce the burden of plastic waste in the environment. The countries have been selected to represent different mixed plastic pollution environments, with specific partners selected which have the expertise and facilities to carry out the necessary technical innovations. Three innovative booster technologies are at the core of this solution accentuating, expediting, and augmenting plastics degradation to levels far in excess of those current achievable. Our approach is a triple-action depolymerisation system where plastic waste will be broken down in three consecutive processes: 1) mechano-biochemical disintegration processes, including a new proprietary sonic-green-chemical technology to reduce the polymer molecular weight of the base polymer to make it amenable to biodegradation; 2) biocatalytic digestion, with enzymes enhanced through a range of innovative techniques including accelerated screening through novel fluorescent sensor and directed evolution; and 3) microbial consortia developed from best in class single microbial strains, which combined leads to highly efficient degradation of mixed plastic waste streams. The outputs from this degradation process will be used as building blocks for new polymers or other bioproducts to enable a new plastic waste-based circular economy.