The overall goal of BE-Rural is to realise the potential of regional and local bio-based economies by supporting relevant actors in the participatory development of bioeconomy strategies and roadmaps. BE-Rural will investigate the particular characteristics of the selected regions at a macro level, as well as existing best practices and business models geared towards the bioeconomy. This higher-level analysis will aid in the assessment of the 'bioeconomy potential' of the selected regions. This work will set the foundation for the implementation of a series of regional Open Innovation Platforms to kick-start the co-creation process, bringing together key stakeholders from academia, policy, business and civil society to develop ideas and capitalise on this bioeconomy potential. Activities will include research & innovation capacity building workshops, educational seminars and webinars, summer schools, and Bio-based Pop-up Stores. Building from this, the proposed 'Network of Knowledge' will aim to share knowledge and lessons learned from the Open Innovation Platforms at an inter-regional level, further disseminating best practices, closing the information gap on issues related to sustainability, and increasing capacities of regional authorities and stakeholders.