The main objective of ST(R)E(A)M IT is to initiate change about the persisting gender inequalities in STEM education, research, and innovation to contribute to the implementation of the ‘The European Manifesto for gender-inclusive STE(A)M education and careers.’ The envisioned aim of the project will be achieved by 1) empowering underrepresented groups in STEM, 2) piloting and fostering the integration of STEAM approaches in STEM education by synthesising previous knowledge and networks, 3) promoting gender-inclusive career paths and increasing the talent pipeline in the STEM fields together with the attractiveness of STEM careers, 4) supporting STEM education providers through knowledge sharing, capacity building to remove gender-based barriers including gender stereotypes in STEM education. By encouraging sustainable collaboration of STEM-oriented businesses, secondary and higher education institutions, research organisations, as well as informal science education establishments, NGOs, and civil society organisations, ST(R)E(A)M IT provides several tools for closing the existing gender gap in STEM education and career.