With 5 million Kg / day of organic pollution produced in Europe (World Bank, 2012 Gani and Scrimgeour, 2014) and climate change, humanity will face a water shortage. Therefore, sustainable management of wastewater and drinking water will go through an anticipation of the pollution and its effects before a major accident. This expectation is based on reliable measurements of both pollutants themselves but especially their effects on biological organisms (toxic and ecotoxic effects of mixtures for example) but that is not the only answer to the problem. Indeed, a global response of the water management also depends on the ability to produce data and to build reliable evaluation of risk scenarios. We propose the creation of a joint laboratory RIMAE to develop and industrialize microbial biosensors capable of measuring the toxic effects in an innovative approach by creating pollution footprint. RIMAE gathers the complementarity of knowledge from the laboratory GEPEA UMR CNRS (CBAC team) specialist in microbial biosensors with the electronics company internationally recognized Tronico-ALCEN to work in complementarity at the interface of their areas of excellence. The hybrid systems that will be developed allow the acquisition of information from living organisms to characterize the toxicity and networks of biosensors will also be deployed in combination with traditional sensors. The aim is to devise a mapping in real time in order to help the management of the natural resource and industrial water. The proximity of the two partners, the complementarity of their approach, their common culture of innovation and research guarantee an ambitious vision in the form of three founding pillars: - To provide the market with technologies from the GEPEA team by using a panel of different microorganisms (bioluminescent bacteria, yeasts, algae) to build a fingerprint of the effluent toxicity. This approach lasting three years will use the expertise of GEPEA but in an industrial logic to ensure a robust solution of the measuring device. - To develop the networking of biosensors by addressing the issues of the transfer of data in a secure manner and in a long distance and the battery life expectancy. The set of biosensors should communicate with existing satellite systems. - To prepare the future of microbial biosensors by extending the concept of pollution footprint to a new mode of action. Including Raman spectroscopic sensors that generate a sophisticated chemical fingerprint for each microorganism. This new approach will develop a "3D vision" of the toxic effect (cells / screening effect / identification of cellular targets).