The objective of this proposal is the organization of a multidisciplinary network (Reliable Diagnostic Point Of Care/ReDiPOC network) to submit a project in the call “Future and Emerging Technologies (FET)” of Horizon 2020. The network will be coordinated by the French partner, Anna-Maria Papini. The European network will be based on a multidisciplinary expertise going from Chemistry & Physics to Biology & Engineering with applications in Biomedical sciences (from bench to bedside). The hard core of the network will aggregate top level European scientists of Universities and SMEs, and will focus on integrating new partners (in the field of diagnostics and clinics) in order to improve the strength of the FET proposal. The financial support asked to the ANR will help to bring the network to life and extend it before writing a proposal with the final aim to guarantee the commercialization of final molecular diagnostics. This will be possible thanks to the collaboration between Universities and SMEs covering the gap between Research & Development. The FET proposal will combine Synthetic Antigenic Probes (SAPs) to newly developed label-free diagnostic devices: 1) the prototype of an electrochemical detection diagnostic "point-of-care" device based on innovative amperometric detections performed in microfluidic channels. 2) nano-sensors integrating high frequency surface acoustic wave devices that provide very precise biomarkers detection in organic fluids. Both technologies: a) will use the adapted SAPs, b) will use IgY antibodies as calibrators, c) will be compared with SAPs-based ELISA using positive and negative sera as controls.