The aim of the Centre for Improving Population Health through E-Health Research (CIPHER) is to carry out research that will improve the health of the nation. It will do this by developing new methods to anonymise, link and analyse healthcare and similar data, to answer a wide range of important research questions. We will often work with researchers who have established large cohort studies, helping them make their cohorts more powerful, longer lasting, and cheaper to operate. E-health research is a new field and so CIPHER will be focussing on training researchers in how to use these data and methods. CIPHER has four core research programmes: The first focuses on developing robust new methods to allow health and other information to be anonymised and analysed. For example, developing ways in which researchers accessing data cannot possibly identify the individuals involved, thereby ensuring that privacy is protected. CIPHER's other three research programmes focus on the impact on people's lives of (1) injury and the built environment; (2) mental health and substance use; and (3) infection. CIPHER researchers will undertake a range of studies to provide better insight into the causes of disease and injury, the consequences of these conditions on individuals and the population, and evaluations of treatments and policies which are designed to improve health. Knowledge of the longer term individual and societal impact of many conditions and treatments is currently very limited, as long term studies are very expensive. CIPHER's work will enable the long term follow up of outcomes using anonymised data, answering these questions effectively but at far less cost. Within its research programmes CIPHER will address many scientific questions, including: How effective are fall-prevention initiatives for older people? What is the impact of giving Vitamin D supplements to people in care homes in reducing hip fractures? Can linked data be used to help Fire and Rescue services prevent more home fires? Have interventions to make homes warmer reduced the number of deaths in winter? How much does substance use in young adults contribute to mental health problems? Does opiate substitution therapy in prison reduce the risk of death following prison release? Can linked routine data be used to identify opportunities to intervene in pathways to harm for people who self-harm or die by suicide? How can information be better used to reduce antibiotic resistant infections? Are the different micro-organisms we carry in our bowels involved in the development of serious health conditions? CIPHER will work with the NHS to develop better ways to measure patients' experiences and treatment outcomes. CIPHER will also develop methods to enable linkage of anonymised treatment data to important social outcomes such as staying in work, continuing in education, or being able to live independently at home. Such information will help the NHS design its services to meet a broader range of patients' needs. CIPHER's believes it is important to communicate effectively with patients, patient groups and the public at large about its research. A significant part of our work therefore will be setting up ways to aid this communication. We will have public representatives involved in our research throughout and they will help guide us and help us communicate effectively with wider groups. CIPHER will be one of a small number of similar Centres that is being set up in the UK and we will be working together to train researchers in these new methods and making sure universities have suitable jobs for them. CIPHER aims to be an internationally recognised centre of expertise in the use of electronic health and associated records for research and, along with other network members, position the UK as the world leader in the field, improving the population's health, increasing UK research income, and improving the economy.

This Fellowship is about re-orientating interactive AI systems, away from systems that might lead to people feeling powerless, redundant and undervalued, turning towards approaches that let people experience joy, creativity, connection and agency as they use AI innovations to amplify their innate abilities, qualities and values. Many everyday people worry about the impact of artificial intelligence on their lives and livelihoods. In the most recent Stanford AI-100 report (September 2021), for example, while the fear of robots taking people's jobs has reduced, there is a strong concern that such systems will erode democracy and values through deep fakes, manipulated social media feeds and the like. The report points to Grand Challenges for AI that involve systems outpacing or outsmarting humans. Even as I write this summary (late Jan 2023), there is a frenzy of excitement over Open AI's ChatGPT, a system that can turn a simple written request (e.g. "Write me a compelling EPSRC summary") into, at least at the surface level, a seductively articulate response (N.B., this summary is definitely written by me). Further, I am writing this while in South Africa where I have engaged with community members in Langa, a township on the outskirts of Cape Town, South Africa, as part of the preparation for the Fellowship. These people spoke of the starkly real problems (from violent crime to very high unemployment). With so many underserved and unheard voices, globally and indeed in the UK, there is a timely and urgent need to think about how to radically enable these "natural intelligences" rather than to replace them with artificial ones. In this Fellowship, then, we will work intensively with people who are not usually involved in AI discovery and innovation - people with lower socio-economic opportunities in the UK and those in Global South communities such as the informal settlements in India, Kenya, Brazil and South Africa. Their lived-experiences will be brought into the design and development process, a process further richly enhanced through the involvement of a diverse set of technology, service provision and creative partners. In doing so, we aim to discover novel ways for people - everywhere, whatever their contexts and opportunities - to engage with AI systems. We call this new trajectory for AI research, EVE - everyone virtuoso everyday - to succinctly summarise the drive of the work. That is, we are interested in defining and evaluating a class of AI technology that enable expressive, individual and masterful interactions, like a virtuoso musician who channels all of their being - physical, mental, emotional and even spiritual - through their instrument to help themselves and others make sense of the world. However, our work is not about turning everyone into an AI-fuelled artist, dancer or musician. Quite the contrary, we look to providing tools that can be deployed in the mundanity of their daily lives. As a Fellowship, the vision and agenda is broad and open to continuous shaping with communities, academics and wider societal stakeholders as the work proceeds over three cycles, each 20 months long, as ideas move from seeds of possibility, growing and being refined into working embodiments, enabling us to evaluate them, integrating them into toolkits for wide impact in academic and practice worlds.

The uneven ways that civil liberties, work, labour and health have all been impacted over the last 18 months as we have all turned to digital technologies to sustain previous ways of life, has not only shown us the extent of inequalities across all societies as they are cut through with gender, ethnicity, age, opportunities, class, geolocation; it has also led many organisations and businesses across all three sectors to question those values they previously supported. Capitalising on this moment of reflection across industry, the public and third sectors; we explore the possibility of imagining and building a future that takes different core values and practices as central, and works in very different ways. As the roles of organisations and businesses across all industry, the public and third sectors changes, what is now taken up as core values and ethos will be crucial in defining the future. INCLUDE+ will build a knowledge community around in/equalities in digital society that will comprise industry, academia, the public and third sectors. Responding to the Equitable Digital Society theme, we ask how we can design, co-create and realise digital services and infrastructures to support inclusion and equality in ways that enable all people to thrive. Focusing on the three connected strands of wellbeing, precarity, and civic culture; we address structural inequalities as they emerge through our research, investigating them through whole system approaches that includes the generation of outputs that comprise of new systems, services and practices to be taken up by organisations. More than this, our knowledge community will be underpinned by empirical, co-curation and participatory led research that will produce real interventions into those structural inequalities. These interventions will be taken up by organisations, responded to and considered, enabling the wider knowledge community to critically assess them in relation to the values they purport to promote. Fed by secondments and supported through smaller exploratory and escalator funds, our knowledge community will not only grow through traditional networking activities such as workshops, annual conferences, academic outputs and further funding; it will also grow through the development of interdisciplinary methods, knowledge exchange practices, and mentorship, which the secondment package will promote. In so doing, we structure our N+ around participatory research practices, people development and knowledge exchange, aiming to grow our network through the development and growth of people and good practice. INCLUDE+ is led by a highly experienced cross-disciplinary team incorporating Management and Business Studies, Computing, Social Sciences, Media and Communication and Legal Studies. Each Investigator brings vibrant international networks; active research projects feeding the Network+; and long experience of impact generation across policy and research. With support from organisations like the International Labour Organisation, Law Commission, Cabinet Office, and Equality and Human Rights Commission as well as the existing DE community, we will develop from and with existing research, extend this work and impact beyond it. Our partner organisations cut across industry, the public and third sectors and include (for example) Lego; NHS AI Lab; Space2; mHabitat; Leeds, Cambridgeshire and Swansea Councils; PeopleDotCom; Ditchley; 5Rights; EAMA; DataKind and IBM. We have designed the Network+ to enable a whole system approach that is genuinely exciting and innovative not just because of scalability, transference and scope, but also because of the commitment to people development, knowledge exchange and interdisciplinary practice that will also shape future research