This research project endeavours to pioneer a biological solution for mitigating carbon dioxide (CO2) emissions from effluent gases produced by bioenergy combustion systems. The primary focus is on converting the captured CO2 into carbon-negative energy carriers, specifically emphasizing the photosynthetic conversion of biogenic CO2 into energy-rich biomass. The transformation of this biomass into widely used renewable energy carriers, such as biocrude and biogas, is targeted, with an additional emphasis on enriching these carriers with renewable hydrogen to achieve carbon circularity. The project is structured to address key aspects, including; efficient biogenic CO2 capture from effluent systems, development of resilient microalgae strains to enhance resistance to flue gas toxicity, novel biomass pre-treatment methods for cell disruption and nitrogen removal (concurrent production of biostimulants), and improvements in the efficiency and sustainability of hydrothermal liquefaction (biocrude), anaerobic digestion (biogas) and hydrogenotropic conversion of CO2 to biomethane. The ultimate goal is to validate the viability of the developed direct CO2 fixation methods through integration with effluent systems at a pilot scale, reaching TRL5. This multifaceted approach underscores the project's commitment to advancing sustainable and efficient methods for biogenic CO2 fixation and subsequent conversion into renewable energy carriers. To assess the economic viability, a detailed techno-economic analysis of the proposed carbon capture and use solution will be conducted. Furthermore, sustainability and social impact assessments will be performed, taking into account circular economy principles and addressing social, economic, and environmental aspects in alignment with the priorities outlined in the European Green Deal.

Algae4IBD's mission is to develop commercial products for Inflammatory Bowel Disease (IBD) prevention and treatment using aquatic natural biological resources. With the emerging developments in natural product, notable success has been achieved in discovering natural products and their synthetic structural analogues with anti-inflammatory activity. However, global biodiversity remains a largely unexploited resource for natural bioactive molecules with an enormous potential for developing commercial products with public health benefits. Micro and macroalgae, found in marine and freshwater, have been identified as promising sources of bioactive compounds including small molecules and secondary metabolites with a wide range of bioactivities as an antioxidant, anti-inflammatory and cancer preventive. Consumption of algae could, therefore, provide defence against chronic inflammatory diseases such as IBD, that until date have no effective cure. This project offers nature to bedside approach, using an entire development along the value chain for a new biodiscovery therapeutic approach by developing and examining algae-based compounds for IBD patients while guaranteeing algae's biodiversity preservation. We propose innovative solutions for increasing the use of algae-based ingredients and to ensure the science-based improvement of nutritional quality and its effect on public health. The researchers, companies and hospitals involved in the different stages of the project will use the biodiversity of algae, both micro and macro, as a wide source for bioactive compounds using state-of-the-art cultivation and extraction technologies for obtaining sufficient amounts of the bio-active molecules together with novel processing protocols. It will result in novel algal-based, high-quality bioactive compounds at GMP grade and lower costs for dual purposes – IBD prevention and treatment in relevance to the food as well as the pharmaceutical industries.

REALM will transform nutrient-rich drain waters from soilless farms into value, by producing microalgae at reduced costs while treating water and capturing CO2 from the air. This concept will increase the circularity and profitability of microalgal production and soilless farming. The NordAqua and ALGACYCLE projects (NordForsk and EEA, respectively) have shown the feasibility of this concept in Finland and Portugal, and now REALM aims to demonstrate it at an industrial scale. Accordingly, two validation facilities will be installed in the Netherlands and Finland, and two demonstration facilities will be deployed in Portugal and Spain near soilless greenhouses. With know-how from the SABANA project (H2020), these facilities will operate photobioreactors under a turbidostatic regime (continuous harvest) for maximum productivity, using nutrient-rich wastewaters from the greenhouses. Growth and harvesting units will be powered by photovoltaic energy and automatically managed by novel sensors, while A.I.-based predictive models and a cloud-based monitoring system will assist production. Microalgal biomass will be processed by local downstream processing units using dairy industry supply chain as a working model. This concept will offer sustainable wastewater treatment technology to farmers by closing the nutrient loop and is expected to reduce microalgae production costs by >50%, whose savings will be used to increase the competitiveness of the proposed microalgae-based products, namely agrochemicals and aquafeed. A business model will be developed to propose the installation of multiple microalgae production facilities, next to soilless greenhouses, and connected to a centralised processing facility. The results generated by REALM will be disseminated so the demonstrated concept can be replicated by relevant stakeholders in all EU, while targeting several objectives established by the European Green Deal, such as working with nature to improve human health by promoting a greener industry.

The overall objective of the AQUAPACK project is the development and evaluation of the effect of novel biodegradable packaging systems on the quality and safety of perishable food and cosmetics in the supply chain of the EU region and worldwide, through the introduction of economically and environmentally sustainable packaging materials based on marine biomass (micro and macro-algae, fish processing side streams and by-catch). AQUAPACK faces the challenge of reducing plastic pollution through transnationally designed innovations for development of novel biodegradable packaging systems. Well-designed secondments between academic and industrial partners with complimentary capacities, will deliver the project objectives: (i) to introduce economically and environmentally sustainable, low carbon packaging materials based on aquatic biomass and side-streams, that can appropriately preserve the quality and safety of food and cosmetics products, from production all the way to consumption. (ii) design and test at least 2 biodegradable packaging materials appropriate for fish fillets and cosmetics, by developing: (i) biodegradable, active films appropriate for food and cosmetics by utilizing aquatic biomass, (ii) biodegradable films appropriate for secondary packaging of cosmetics. (b) An innovative direct freshness monitoring system (biosensor) applicable across the supply chain of perishable products. (iii) to improve the sustainability of the food and cosmetics sectors by preserving their quality, extending their shelf life and thus reducing waste. (iv) reduce waste of packaging materials by applying non-plastic, biodegradable packaging solutions for food and cosmeceutical products. (v) assess the sustainability and safety of the new packaging solutions in comparison to commonly used packaging for food and cosmetics. (vi) to provide cross-cutting interdisciplinary knowledge exchange, technology transfer and training to improve employability and career prospects.