The CLEANDEM project, with its collaboration of 11 partners from 4 EU countries, proposes a technological breakthrough associated to various dismantling and decommissioning (D&D) operational steps with an Unmanned Ground Vehicle (UGV) Platform. The CLEANDEM strategy will be based on innovative detection technology systems that will constitute a toolbox for equipping an intelligent robotic platform for fully remote operations. The pre-identified technologies are low-cost sensThe CLEANDEM project, with its collaboration of 11 partners from 4 different EU countries, proposes a technological breakthrough for dismantling and decommissioning (D&D) operations of nuclear sites, employing an Unmanned Ground Vehicle (UGV) Platform equipped with innovative radiological sensing probes. The aim of the project is to deliver a cyber physical system which will support the end-users’ operations, initially performing a radiological assessment of the area and then monitoring D&D operations throughout the final characterization of the plant. This will result in a 3D and fully detailed digital twin of the surveyed area augmented with radiological information provided by the sensors, thus enabling an efficient and effective planning of the dismantling actions and optimizing the nuclear waste sorting for reprocessing or for delivery to the final storage. Targeted impacts of the UGV Platform are to: save time, drastically reduce costs, minimize human intervention, improve workers and population safety and be greener; all of those driving the project execution to match the stakeholders’ expectation. The effectiveness of the UGV Platform will be assessed in an extensive testing and validation campaign that will be performed in laboratories, in simulated environment and finally on the field. A demonstration event in a real nuclear site, involving all project partners and external stakeholders, will conclude the three years project activities opening for further exploitation in the D&D market.