The main aim of Epistemology in Art, Science, Technology (EpisTeaM) is to develop a collaborative consortium and intersectoral network to test the hypothesis that diversification of epistemological positions could be the key to responsible Epistemology in Technological Education and Innovation. The fundamental problem being addressed is the impact of digital technologies on the construction of knowledge and truth, an ‘epistemic crisis’ inside and outside academia. Epistemology is explored as cultural Episteme, disciplinary Epistemology and whole experimental approach. Epistemological diversification through transdisciplinary research is essential and will be investigated through the intersections of Art, Science and Technology by an expansion of the concepts Techne, technics and Technology in the context of disciplinary activity. In the contemporary context of globalised computational conditions, the question of the impact of digital technologies on knowledge is often understood as misinformation and post-truth, however, there is also an inbuilt epistemological conditioning taking place through the digital technologies themselves. For this purpose, a large transdisciplinary research mobility is necessary in order to understand the localised contextualisation of digital technologies within the disciplines, cultures and research laboratories. The traditional epistemological frameworks and paradigms are currently challenged by globalised computational models, where reason itself has been reduced to calculation and probability. EpisTeaM will explore and challenge this dominant epistemological claim. Just as a biodiversity is necessary for the future sustainability of the planet, so too is a Technodiversity within the Technosphere of globalised computation. The partners are from the European University of Technology (ECT Lab+), USA, India and non-academic partners in Europe (SME and Public Bodies).