The STOP project will bring together an interdisciplinary and intersectoral group of subject matter experts from industry and academia under one umbrella, to address the health societal challenge of obesity with the specific objectives of mitigating the enormous and growing Health Care costs of obesity and related health issues (like heart disease, diabetes, arthritis, liver disease, gallstones, cancer, dementia) that burden European citizens. The STOP project will address this need through the foundation of an innovative platform to support persons with obesity with a better nutrition under supervision of healthcare professionals. Therefore, the STOP platform will capture various PwO data from different kind of smart sensor streams and chatbot technology, manage and enrich available data with existing knowledge bases and fuse these by machine learned driven data fusion approaches for sophisticated AI data analysis. Essentially, this gathered and analysed data and knowledge is accessible and usable for Health Care professionals amongst others as input for a gamification approach to teach PwO healthier nutrition. In the STOP validation an app that establishes an analogy to Dorian Gray mirror, teaching healthier nutrition.

GenDAI will leverage metagenomic potential to deliver powerful diagnostic results facilitating the development of Personalized Medicine, addressing assay research and development as well as productive clinical diagnostics in a comprehensive way by creating a highly innovative medical diagnostics platform that supports microbiome profiling with novel biomarkers using Artificial Intelligence (AI). This innovative platform will allow clinicians to assess and monitor patients while complying with strict regulatory requirements of laboratory diagnostics. Ultimately, GenDAI will contribute to accelerate conversion of innovative ideas and technology solutions into breakthroughs in medical analyses services. Delivery of GenDAI tangible outputs will be driven by the following Research and Innovation Objectives: a) Create new metagenomic datasets containing microbiome samples from stool of patients under informed consent suffering from inflammatory bowel disease (IBD); b) Develop and integrate the GenDAI Diagnostics Workflow, focusing on implementing a fully automated data processing pipeline; c);Provide a robust, cloud-based foundation for the development of the platform that integrates advanced data management and knowledge infrastructure focusing on security, reproducibility and long-term archiving (GenDAI Safe); d) Develop and improve AI methods to identify relevant biomarkers and classify corresponding metagenomic sequences in order to characterise microbiome profiles to provide a personalised diagnostic result of patients’ state of health (GenDAI Discovery); e) Deliver innovative visual user interfaces and interactive clinical reporting (GenDAI Interactive Reporting) and f) Deliver the marketable, regulatory compliant GenDAI technology and tool suite.