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SUPERSONIC IMAGINE

SUPERSONIC IMAGINE

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6 Projects, page 1 of 2
  • Funder: French National Research Agency (ANR) Project Code: ANR-23-CE19-0040
    Funder Contribution: 504,308 EUR

    The first objective of the FATUS project is to lift the lock on the quantification of intramuscular fat content by ultrasound thanks to an innovative beamforming method. A validation step by MRI will confirm the achievement of this objective by developing specific sequences for fat quantification. By knowing and mapping these infiltrates, the third objective is to better understand the mechanical behavior of muscles in the presence of fat by improving ultrasound elastography techniques. The fourth objective is oriented around a characterization and a three-dimensional quantification of the muscles. The last objective is to provide a first clinical applications for the diagnosis of muscle sarcopenia due to aging. This multidisciplinary project therefore proposes to start from innovations in the field of ultrasonic medical imaging, to move towards a better fundamental understanding of the 3D behavior of the muscle, then towards clinical applications for a particularly important disease for old people. In order to carry it out, we have brought together a multidisciplinary team of researchers who are leaders in their fields (physics, industry, biomechanics, medicine).

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  • Funder: French National Research Agency (ANR) Project Code: ANR-10-NANB-0001
    Funder Contribution: 1,344,000 EUR
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  • Funder: European Commission Project Code: 731877
    Overall Budget: 3,815,260 EURFunder Contribution: 3,815,260 EUR

    SOLUS is a trans-disciplinary 54-month project bringing together 9 partners: industries (4), academic and clinical institutions from 5 countries (engineers, physicists and radiologists) representing cutting-edge expertise in their fields, to develop an innovative non-invasive, point-of-care, low-cost, easy-to-operate, multi-modal imaging system (diffuse optics and ultrasounds/shear wave elastography) for high-specificity diagnosis of breast cancer, the most common female cancer in Europe. Mammographic screening is effective in reducing mortality, however the 10-year cumulative false-positive risk is 50-60%, leading to needless additional invasive procedures (e.g. biopsy). The project addresses the unmet clinical need for higher specificity in breast cancer imaging following screening by fully combining photonics with non-photonics techniques, developing and clinically validating innovative and previously unthinkable photonics concepts and components: time-domain small source-detector distance optical tomography, miniaturized picosecond pulsed laser sources, high-dynamic-range time-gated single-photons detectors to achieve unprecedented sensitivity and depth penetration. For the first time, this allows a comprehensive quantitative characterization of breast tissue including composition (water, lipids, collagen), functional blood parameters, morphologic information and mechanical parameters (stiffness). This innovative multi-parametric characterization will significantly improve the specificity of breast screening, with great impact on the quality of life of millions of European women every year, and huge savings for the healthcare systems. The strong involvement of leading industrial players at all levels in the value chain will push the European innovation process and make a significant contribution to ensuring Europe’s industrial leadership in the biophotonics healthcare market, while addressing one of the largest societal challenges in health and well-being.

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  • Funder: French National Research Agency (ANR) Project Code: ANR-19-STHP-0003
    Funder Contribution: 2,255,910 EUR
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  • Funder: French National Research Agency (ANR) Project Code: ANR-16-RHUS-0003
    Funder Contribution: 6,600,000 EUR
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