The primary aim of ReSolve is to replace the hazardous solvents toluene and N-methyl-2-pyrrolidone (NMP) with safe alternatives derived from non-food carbohydrates. Starting from promising bio-based platform molecules, an effective combination of computational modelling, high-throughput toxicity testing and evaluation of application performance will be used to design bespoke bio-based solvents. New structures will not contain the toxic aromatic or N-alkylamide functionalities that make toluene and NMP substances of very high concern. At least one primary apolar and one primary dipolar aprotic substitute for toluene and NMP respectively will be targeted. These solvents will be designed to serve a wide range of applications, will be brought to pilot-scale production at TRL 5. Their sustainability, low health impact and high application performance will also be demonstrated. The provision of safe and economically viable bio-based solvents by ReSolve will allow the full benefit of regulatory restrictions on the use of aromatic and nitrogen-containing solvents to be felt without a negative impact on the economic security of the European solvents industries. The impact of this research is also relevant to thousands of downstream businesses and consumers that are dependent on solvents. Above all, it will positively affect the health and safety of the millions of European citizens who are routinely exposed to solvents as part of their job. Additionally, ReSolve is set-up to produce a pipeline of new solvent candidates meaning that not only will a couple of candidates be taken to TRL 5, but many more candidates for specific applications will also be progressed to TRL 3-4, thus offering greater substitution options for hazardous solvents in the near future.

The objective of CHAMPION is to develop and demonstrate that novel bio-based polymers can be efficiently synthesised and applied in high-performance applications, beyond plastics, where the current petrochemical-derived materials are not fully fit for purpose. Technologies to be developed in CHAMPION include the reductive amination of bio-based chemicals to create novel sustainable diamine monomers, application of aza-Michael chemistry onto fully bio-derivable polymers, and bio-based unsaturated polyesters from secondary alcohol diols on a kilogram scale. The new materials will be specifically circular by design and assessed as such, thus making them superior to current materials by ensuring that (chemical) recyclability or biodegradability are possible. Applications will be tested by four relevant industry end-users in the coatings, textiles, home care formulation, and structural adhesives sectors. Up to 12 bio-based materials will be subject to advanced performance testing after preliminary screenings of many more candidates. The toxicity of materials, their precursors, and break-down products (e.g. during biodegradation) will be evaluated, as well as the environmental, economic, and social impact of the new bio-based value chains these materials create (safe by design). A cradle-to-grave sustainability assessment will use the benchmarks set by commercial products to quantify performance, resource efficiency, and reduced greenhouse gas emissions. The producers of two bio-based chemical intermediates in the consortium will form new cross-sector interconnections with the four end-users creating increased business and job opportunities. Dissemination and exploitation of results will be conducted to establish the basis of new value chains and inform Standards fit for describing new applications of bio-based products. At least two bio-based materials are targeted to reach TRL 5, with others in the pipeline for further development as part of the legacy of the project.