
GLAXOSMITHKLINE VACCINES SRL
GLAXOSMITHKLINE VACCINES SRL
29 Projects, page 1 of 6
assignment_turned_in Project2014 - 2016Partners:GLAXOSMITHKLINE VACCINES SRLGLAXOSMITHKLINE VACCINES SRLFunder: European Commission Project Code: 623168more_vert Open Access Mandate for Publications assignment_turned_in Project2015 - 2019Partners:Leiden University, University of Rijeka, CIC BIOGUNE, GLAXOSMITHKLINE VACCINES SRL, INSTITUTO DE MEDICINA MOLECULAR +7 partnersLeiden University,University of Rijeka,CIC BIOGUNE,GLAXOSMITHKLINE VACCINES SRL,INSTITUTO DE MEDICINA MOLECULAR,University of Manchester,LMU,UNIMI,MPG,GLYCOUNIVERSE,CNRS,MEDRIFunder: European Commission Project Code: 675671Overall Budget: 3,554,500 EURFunder Contribution: 3,554,500 EURGLYCOVAX is a network for the education of promising young scientists who will learn how to rationally design a next generation of well-defined and innovative glycoconjugate vaccines to improve current preventive therapies and to tackle unmet medical needs. Glycoconjugate vaccines represent the key for success of vaccination in children. The covalent linkage to proteins renders carbohydrates able to evoke a T-cell memory response. Current vaccines are prepared from heterogeneous mixtures of sugars linked by unspecific methods to the carrier protein giving complex mixtures of products. Due to this intricate structure, it has not been possible to apply a medicinal chemistry approach in the development of glycoconjugate vaccines and to fully understand their mechanism of action. Combination of novel approaches for glycan synthesis and site-selective conjugation methods now gives access to conjugates defined in sugar component and attachment site, thus leading to robust structure-immunogenicity relationship. Advancements in structural biophysics can be applied to select the optimal glycan antigen. By combining the beneficiaries’ expertise in carbohydrate synthesis, bioconjugation, high throughput screening, structural glycobiology, vaccinology and immunology, together with the experience in project management, GLYCOVAX will create a multidisciplinary environment where 14 young researchers will contribute to develop a novel route towards improved, safer and better characterized glycoconjugate vaccines, and contemporarily acquire transferable skills which will lead them to become the new leaders of academic or industrial research. The network will involve 9 academic groups and 2 industrial partners as Beneficiaries, and one SME as Partner Organization. The profound interaction between academy and industry will aid the students to get new concepts and visions for translating their ideas from the bench to the manufacturing of the next generation of glycoconjugate vaccines.
more_vert assignment_turned_in Project2014 - 2018Partners:EPFL, UCC, GLAXOSMITHKLINE VACCINES SRLEPFL,UCC,GLAXOSMITHKLINE VACCINES SRLFunder: European Commission Project Code: 612219more_vert Open Access Mandate for Publications assignment_turned_in Project2011 - 2017Partners:deCODE Genetics (Iceland), Imperial, ALTA SRLU, ABERA BIOSCIENCE, Utrecht University +47 partnersdeCODE Genetics (Iceland),Imperial,ALTA SRLU,ABERA BIOSCIENCE,Utrecht University,CNRS,KCL,SIGMOID,VLS,UOXF,VLS,PEVION BIOTECH AG,CEA,LUMC,DUOTOL,ARENAVAX,TBVI,VLA,DH,VISMEDERI SRL,MICROBIOTEC SRL,SSI,SEATTLE BIOMED,BTG,Institut Pasteur,Emory University,CBB,WHO,IRB,GU,Hookipa Biotech AG,REITHERA SRL,VACCIBODY AS,GSK Bio,Xbrane Biopharma (Sweden),University of Innsbruck,MPG,SVA,ERASMUS MC,GLAXOSMITHKLINE VACCINES SRL,Fondazione Humanitas per la Ricerca,SGUL,GSK VACCINES INSTITUTE FOR GLOBAL HEALTH SRL,HEALTH PROTECTION AGENCY HPA,University of Surrey,UNIGE,OAW,UNISI,ISS,IDRI,Hookipa Biotech AG,MEND FRANCFunder: European Commission Project Code: 280873more_vert assignment_turned_in Project2015 - 2020Partners:EUROPEAN VACCINE INITIATIVE, PEI, UOXF, EU, AstraZeneca (Sweden) +20 partnersEUROPEAN VACCINE INITIATIVE,PEI,UOXF,EU,AstraZeneca (Sweden),SVA,Seqirus,DH,University of Surrey,University of Bergen,UNISI,QUINTEN,ISS,Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico,Ghent University, Gent, Belgium,GLAXOSMITHKLINE VACCINES SRL,GSK Bio,SANOFI PASTEUR SA,ERASMUS MC,ABBOTT,ARTEMIS ONE HEALTH RESEARCH BV,Janssen Vaccines (f.k.a. Crucell Holland B.V.),BPRC,University of Perugia,EMEAFunder: European Commission Project Code: 115672more_vert
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