UK policy is for safe, personalised maternity care. However, during COVID-19 tests and visits have been reduced in some places, and some women with worrying symptoms are not going to hospital. Other places are trying new solutions, including remote access technologies. Some Trusts have reduced community maternity services, including home and birthcentre births; barred birth companions in early labour; and separated mothers, babies, and partners during labour, and in neonatal units. There are reports of women giving birth at home without professional help, possibly due to fear of infection, or of family separation. In contrast, the Netherlands has a policy of increased community maternity services during COVID-19. We want to find out how best to provide care for mothers, babies, and partners during and after a pandemic. We will look at what documents and national leads say about service organisation in the UK and the Netherlands, and at women's and parents experiences. We will also look in detail at what happened in 8 UK Trusts during the pandemic. We will find out how their services have been organised during COVID-19, what parents and staff think, and what the outcomes are, including infections. We will then share the findings with key stakeholders to agree a final organisational model that can be used to ensure safe, personalised routine and crisis maternity care, now, and in future. This will include useful resources and links relating to innovative best practices that we find out about during the study.

Artificial Intelligence (AI) has advanced rapidly over the last five years, largely as a result of new algorithms, affordable hardware, and huge increases in the availability of data in digital form. The UK has recognised as a national priority the urgent need to exploit AI in human health, where digital data is being created from many sources, for example: images from tissue slices, X-ray devices, and ultrasound; along with laboratory tests, genetic profiles, and the health records used by GPs and hospitals. The potential is enormous. In future, AI could automatically identify those at risk of cancer before symptoms appear, suggesting changes in lifestyle that would reduce long-term risk. It could greatly speed-up and increase the reliability of diagnostic services such as pathology and radiology. It could help doctors and patients select the most appropriate care pathway based on personal history and clinical need. Such improvements will lead to better care and more cost-effective use of resources in the NHS. Our Centre for Doctoral Training will train the future researchers who will lead on this transformation. They will come from a variety of backgrounds in science, engineering and health disciplines. When they graduate from the Centre after four years, they will have the AI knowledge and skills, coupled with real-world experience in the health sector, to unlock the immense potential of AI within the health domain. Our scope is on AI for medical diagnosis and care with a focus on cancer for which there are particularly rich sources of digital data, and where AI is expected to lead to significant breakthroughs. Leading with cancer, we will inform the use of AI in medical diagnosis and care more widely. The Centre will be based in the City of Leeds, which has developed into the home of the NHS in England. The University of Leeds and the Leeds Teaching Hospitals Trust (LTHT), working with key national partners from the NHS and industry, provides the ideal environment for this Centre. There is internationally excellent research on AI and on cancer, including a world leading centre for digital pathology. There is already strong collaboration between the different organisations involved. The Centre builds on a well-established track record in transferring research ideas into world-leading clinical practice and new products. Our graduates will become international leaders in academia and industry, ensuring the UK remains at the forefront in health research, clinical practice and commercial innovation.

In recent years, cultural institutions have supported public wellbeing (e.g. increasing offers of activities and volunteering opportunities) and can be considered 'community assets' that are central to social prescribing. Social prescribing aims to empower people to address 'non-medical' challenges (e.g. isolation, anxiety, low mood) that affect how they feel physically and psychologically. The NHS has seen the introduction of link workers, employed to work in GP practices to facilitate social prescribing by connecting people to community assets (e.g. groups, organisations, charities). This might include connections to cultural institutions, which can ameliorate social isolation and give people a focus away from their worries. The COVID-19 pandemic is affecting what the cultural sector can offer, at a time when significant mental and/or social consequences of the crisis are anticipated, especially among older people. From the outset, this population was identified as 'at risk' from the condition itself and responses to it, including extreme isolation, especially if unfamiliar with online communication. Our research will explore how cultural institutions adapt to support older people's wellbeing. This will allow us to provide recommendations on being 'referral-ready'[1] cultural institutions for social prescribing for older people in the context of the current pandemic and future ones. We will use a realist approach to explore what works, for whom, why and in what circumstances. We will synthesise existing evidence to develop a programme theory on how cultural institutions might be best mobilised and engaged to support older people's resilience during and after the pandemic. We will refine this programme theory by testing it through further data collection: interviews with older people/cultural institution staff and survey with link workers.

In the UK one in two people are diagnosed with cancer during their lifetimes and of those who survive 41% can attribute their cure to a treatment including radiotherapy. Proton beam therapy (PBT) is a radical new type of radiotherapy, capable of delivering a targeted tumour dose with minimal damage to the surrounding healthy tissue. The NHS is investing £250m in two new "state of the art" PBT centres in London and Manchester. In addition, Oxford has attracted £110m (from HEFCE and business partners) for its new Centre for Precision Cancer Medicine, incorporating PBT. This EPSRC Network+ proposal seeks to bring the EPS community together with clinical, consumer and industrial partners and develop a national research infrastructure and roadmap in proton therapy. It capitalises on ~£300m of government investment and affords an opportunity for those not directly involved in the new proton centres to be actively involved in the national research effort in this area. This project has the backing of NCRI Clinical and Translational Radiotherapy Working Group and NHS England and will work with the national Proton Physics Research and Implementation Group of the National Physical Laboratory. It also involves industrial stakeholders, consumer groups and international partners (including PBT centres in Europe and USA and CERN). While PBT offers patients many advantages it also presents a wealth of technical challenges and opportunities where there is an unmet research and training need. This is where there the involvement of the EPS community is vital since this challenge in Healthcare Technologies requires expertise from across the EPS spectrum and maps on to themes in ICT, Digital Economy, Engineering, Mathematics, Manufacturing the Future, and the Physical Sciences and also finds synergies within quantum technologies. It directly maps onto the cross cutting capabilities identified in the Healthcare Technologies Grand Challenges. This is a highly multi-disciplinary area at the frontiers of physical intervention, which achieves high precision treatment with minimal invasiveness. This Network+ is particularly timely; it will afford the UK the opportunity to develop a world-leading research capability to inform the national agenda, capitalising on existing research excellence and the synergies that can be developed by bringing the clinical and EPS areas together. It will also collaborate with existing doctoral training provision to train the next generation of leaders where a national need has been identified. This proposed Network+ will create a national infrastructure to meet a national research and training need and will allow the UK community to work together in the multi-disciplinary field of proton research. This proposed Network+ will create a sustainable national proton beam infrastructure by drawing together sites where proton beams are already available (albeit at lower energies) and providing a route for the research community to access these facilities. As the new proton centres come on line they will add to this national resource and the centres will work together to provide a virtual national infrastructure for the UK, which by the end of the Network+ will be fully sustainable. The Network+ will also provide a route for those interested in the field but not requiring proton experiments to become involved. In addition, the Network+ will offer secondments ("Discipline Hops") into the clinical environment in both the UK and in PBT centres overseas. Working with NHS England the Network+ will develop a PBT training scheme. This will link the existing NHS provision with EPSRC Centres for Doctoral Training and allow equivalencies to be established and so provide a "fast track" to a skilled workforce and the next generation of leaders. The Network+ will also seek to engage with industry through joint research and secondments and with consumer groups, policy makers and the general public.

The coronavirus pandemic has seen a huge increase in the availability of resources designed to inspire and connect us during lockdown. From online singing groups and art classes, to guides for engaging creatively with nature from your window, garden or local park, there are hundreds of resources designed to combat isolation and stimulate creativity at home. We want to understand how participants engage with these initiatives, such as the Get Creative campaign. We want to know the positive and negative aspects of engaging with creative resources whilst at home, and how this affects participants' lives, their health and their wellbeing. We want to know what works, how and why, so that we can make recommendations about the key ingredients for high quality resources. We will use participant feedback to generate guidance for organisations to use to help people in their communities, through for example harnessing the power of volunteers to support people who may be less able to access online resources, and we will provide guidance regarding safeguarding, facilitation and accessibility. Finally, by working with participants, providers and partners we will use the learning from this project to enable organisations to support their communities as they adapt to post-lockdown Britain.