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TUC

Clausthal University of Technology
26 Projects, page 1 of 6
  • Funder: European Commission Project Code: 101135402
    Overall Budget: 4,644,950 EURFunder Contribution: 4,644,950 EUR

    Currently there are no portable test or biosensors validated for air, soil or water quality control for pathogens, Chemicals of Emerging Concern (CECs) and Persistent Mobile Chemicals (PMCs), so such devices are much awaited by all stakeholders to ensure successful control and prevention of contamination and infections. Mobiles consortium will develop an interdisciplinary framework of expertise, and tools for monitoring, detection, and consequently mitigation of pollution from pathogens, CECs, PMCs, thus benefiting human and environmental health. Mobiles consortium will work to achieve the following objectives: Develop electronic biosensors for monitoring organic chemicals (pesticides, hormones) and antimicrobial resistance bacteria and pathogens in water, soil and air; Develop organism-based biosensor for detection of organic and inorganic pollution in water and soil; Study environmental performance of developed organisms and devices; Metagenomics analysis of organisms leaving in polluted areas in order to enable searches for diverse functionalities across multiple gene clusters Perform safety tests (e.g., EFSA) to assess the impact of developed organisms on the natural environment. Organism-based biosensor will consist on genetically modified chemiluminescent bacteria able to detect antibiotics, heavy metals, and pesticides in water; genetically modified plants that will change colour when in the soil is present arsenic; and marine diatoms that will be used to detect bioplastic degradation in marine and aquatic environments. Developed devices and organisms will be implemented by using flexible technologies, which can guarantee an easy adaptation to other biotic and abiotic pollutants. Devices and organisms, after proper validation and approval, could be used by consumers, inspection services and industry operators, as well as environmental emergency responders to monitor and detect PMCs, CECs and pathogens in water, air and soil

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  • Funder: European Commission Project Code: 245355
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  • Funder: European Commission Project Code: 218037
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  • Funder: European Commission Project Code: 101062517
    Funder Contribution: 173,847 EUR

    Food allergies affect around 26 million of Europeans and 32 million of Americans. The severity of the allergic reaction may vary from less severe symptoms such as hives and digestive problems, to a quickly progressing and potentially life-threatening anaphylactic shock. Nowadays, food allergy is an incurable condition, so the most important preventive measure is the complete abstinence from the allergen. Existing allergen detection methods are slow, cumbersome, costly, and most of them are limited to work in a lab environment. The RESAS project’s goal is to fabricate a device able to sense extremely low concentrations of food allergens within minutes. This is achieved by combining an ultra-high sensitive biosensor substrate, an integrated optical transducer and an electrical signal processing unit. The proposed kind of sensor on the basis of integrated optics enables small size (5 cm3), high repeatability and instant response, as well as potentially low-cost and mass production. This is achieved thanks to the RoF technology and the signal analysis of the output laser of the SPR in the electrical domain, which reduces instrumentation demands with instant allergen detection and great biosensing sensitivity. Furthermore, the RESAS device has a removable biosensing substrate that can be replaced after use, allowing users to operate RESAS several times and for as many types of food allergens as needed. This approach of interchangeable biosubstrates tackles one of the major limitations of most current biosensing technologies, which can be used only once and are restricted to one type of food allergen. The RESAS project will significantly impact the food industry, as our food allergen testing method promises to be quick, effective, and inexpensive. This may lead politicians to demand a more rigorous testing regime, greatly improving food safety. Finally, a new class of portable test devices for millions of allergists and end-users will be created.

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  • Funder: European Commission Project Code: 232665
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