The overall objective of Stance4Health is to develop a complete Smart Personalised Nutrition (SPN) service based on the use of mobile technologies as well as tailored food production that will optimize the gut microbiota activity and long-term consumer engagement. The Stance4Health consortium consists of 19 partners from 8 European countries (Spain, Germany, Denmark, Romania, Italy, Greece, Belgium, UK). Six SMEs will be in charge of the development and future commercialisation of the novel SPN service, including 2 new apps for personalised nutrition, integration of a wearable device for daily analysis of one’s body composition, 9 tailored cereal-derived foods for specific (vulnerable) consumer groups (overweight, coeliac disease or food allergy, adults, children), 6 individualised dietary supplements for adults, and 1 nutraceutical and 1 in vitro diagnostic test to control the gut microbiota activity. These novel tools and services have the potential to directly impact more than 67 million European adults and 8 million children by 2022, at a monthly cost of only 0.99€ (for the app).