Mobile laboratories are becoming increasingly important for quick response to epidemic outbreaks in remote areas. Due to climate change and rising temperatures, emerging arboviruses (Crimean-Congo haemorrhagic fever virus, West Nile Virus, Rift Valley fever, Dengue fever) are finding their way into Europe through arthropod vectors (mosquitoes, ticks), and are becoming a major public health concern. Optimally monitoring zoonotic outbreaks requires a "One Health" approach, in which not only human, but also animal and environmental samples are analysed, as close as possible to the vectors' habitat. Also returning travellers might carry haemorrhagic Ebola/Marburg virus or respiratory pathogens such as SARS-CoV-2. A survey of existing European mobile laboratory capacity revealed several shortcomings: of 193 labs, 66% were civilian, 88% were exclusively for human diagnostics, with 11% having an accredited quality management system, and only 3% had the highest bio-safety level BSL-4 needed for (haemorrhagic) arbovirus handling. MOBILISE aims to close this diagnostic gap, by developing a novel, quality-assured, mobile One Health laboratory solution, to provide BSL-4 capacity to many European countries. It will receive human/animal/environmental samples for molecular diagnostics, serology, microbiology, and host a whole genome sequencing platform for pathogen discovery and epidemiological analysis. We will further develop novel rapid diagnostic tests for BSL-3/4 pathogens, and produce results in machine-readable form. A novel AI-based "Emergency Operating Centre and Decision Support System" software will assist end-users in coordinating MOBILISE fleets across Europe and manage outbreaks in real-time. Hosted on an electric/hybrid truck platform, and using solar and wind-energy, it will also reduce CO2 emissions in compliance with the European Green Deal. The lab will be field-tested to TRL-7 by National agencies and first-responders in Austria, Romania, Greece and Africa.

STAMINA develops an intelligent decision support toolset for pandemic prediction and management and demonstrates its use by practitioners at national and regional levels within and across EU borders. The STAMINA toolset enables national planners and first responders to anticipate and respond to the the “known-unknowns” in their daily effort to enhance health security. Main functionality of the toolset includes: • Real-time web and social media analytics aiming at public trust monitoring and flagging possible disease outbreaks • POCT and smart wearable diagnostic devices for first line screening • Predictive modeling of pandemic outbreak and its impact, along with decision-making support in implementing mitigation strategies, • Early Warning System • Crisis management tool defining the roles and actions of key actors during crisis management • Scenario Generation tool for creation of training scenarios • Common Operational Picture as the main interface of the solution enabling timely and coordinated response The toolset is accompanied by a set of Guidelines on effective implementation of risk communication principles and best practices in cross-organisational preparedness and response plans. The use of the STAMINA toolset will be demonstrated through 12 national and regional small-scale demonstrators and one large-scale cross-border simulation exercise involving all consortium partners.