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- Data Repository United Kingdom Compatibility:Not yet registeredPartners:University of Oxford Biotherapeutics, Structural Biology, immunoglobulin complex, circulatingUniversity of Oxford
The Therapeutic Structural Antibody Database tracks all antibody- and nanobody-related therapeutics recognized by the World Health Organisation (WHO), and identifies any corresponding structures in the Structural Antibody Database (SAbDab) with near-exact or exact variable domain sequence matches. Thera-SAbDab is synchronized with SAbDab to update weekly, reflecting new Protein Data Bank entries and the availability of new sequence data published by the WHO. Each therapeutic summary page lists structural coverage (with links to the appropriate SAbDab entries), alignments showing where any near-matches deviate in sequence, and accompanying metadata, such as intended target and investigated conditions. Thera-SAbDab can be queried by therapeutic name, by a combination of metadata, or by variable domain sequence - returning all therapeutics that are within a specified sequence identity over a specified region of the query. The sequences of all therapeutics listed in Thera-SAbDab are downloadable as a single file with accompanying metadata.
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For further information contact us at helpdesk@openaire.eu - Data Repository United States Compatibility:Not yet registeredPartners:Department of Environmental and Public Health Sciences, University of Cincinnati Life Science, Epigenomics, ToxicologyDepartment of Environmental and Public Health Sciences, University of Cincinnati
The Chromium Epigenomics Toxicology (EpiCrDB) database contains a variety of epigenomics experimental assays relating to research on how Cr(VI) perturbs chromatin organization and dynamics. This data is used in reseach into how its toxicity may be attributed to epigenetic carcinogenicity. Manually-annotated sample and experiment metadata is included to facilitate FAIR data access. Hexavalent chromium [Cr(VI)] compounds are well-established respiratory carcinogens utilized in industrial processes. While inhalation exposure constitutes an occupational risk affecting mostly chromium workers, environmental exposure from drinking water contamination is a widespread gastrointestinal carcinogen, affecting millions of people throughout the world. The mechanism of action of Cr(VI) at the molecular level is poorly understood.
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Relative evolutionary importance of amino acids within a protein sequence.
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re3data: r3d100011870
IndExs is a database comprising information on exsiccatae (=exsiccatal series) with titles, abbreviations, bibliography and provides a unique and persistent Exsiccata ID for each series. Exsiccatae are defined as "published, uniform, numbered sets of preserved specimens distributed with printed labels" (Pfister 1985). Please note that there are two similar latin terms: "exsiccata, ae" is feminine and used for a set of dried specimens as defined above, whereas the term "exsiccatum, i" is neutral and used for dried specimens in general. If available, images of one or more examplary labels are added to give layout information. IndExs is powered by the Diversity Workbench database framework.
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re3data: r3d100010580
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For further information contact us at helpdesk@openaire.eu - Data Repository United States Compatibility:Not yet registeredPartners:University of Illinois at Urbanan-Champaign, Prairie Research Institute Life Sciences, Agriculture, Forestry, Horticulture and Veterinary Medicine, Natural SciencesUniversity of Illinois at Urbanan-Champaign, Prairie Research Institute
re3data: r3d100011669
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re3data: r3d100010629
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- Data Repository United Kingdom Compatibility:Not yet registeredPartners:University of Oxford Biotherapeutics, Structural Biology, immunoglobulin complex, circulatingUniversity of Oxford
The Therapeutic Structural Antibody Database tracks all antibody- and nanobody-related therapeutics recognized by the World Health Organisation (WHO), and identifies any corresponding structures in the Structural Antibody Database (SAbDab) with near-exact or exact variable domain sequence matches. Thera-SAbDab is synchronized with SAbDab to update weekly, reflecting new Protein Data Bank entries and the availability of new sequence data published by the WHO. Each therapeutic summary page lists structural coverage (with links to the appropriate SAbDab entries), alignments showing where any near-matches deviate in sequence, and accompanying metadata, such as intended target and investigated conditions. Thera-SAbDab can be queried by therapeutic name, by a combination of metadata, or by variable domain sequence - returning all therapeutics that are within a specified sequence identity over a specified region of the query. The sequences of all therapeutics listed in Thera-SAbDab are downloadable as a single file with accompanying metadata.
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For further information contact us at helpdesk@openaire.eu - Data Repository United States Compatibility:Not yet registeredPartners:Department of Environmental and Public Health Sciences, University of Cincinnati Life Science, Epigenomics, ToxicologyDepartment of Environmental and Public Health Sciences, University of Cincinnati
The Chromium Epigenomics Toxicology (EpiCrDB) database contains a variety of epigenomics experimental assays relating to research on how Cr(VI) perturbs chromatin organization and dynamics. This data is used in reseach into how its toxicity may be attributed to epigenetic carcinogenicity. Manually-annotated sample and experiment metadata is included to facilitate FAIR data access. Hexavalent chromium [Cr(VI)] compounds are well-established respiratory carcinogens utilized in industrial processes. While inhalation exposure constitutes an occupational risk affecting mostly chromium workers, environmental exposure from drinking water contamination is a widespread gastrointestinal carcinogen, affecting millions of people throughout the world. The mechanism of action of Cr(VI) at the molecular level is poorly understood.
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For further information contact us at helpdesk@openaire.eu - Data Repository United States Compatibility:Not yet registeredPartners:BCM Life Science, Evolution, proteinBCM
Relative evolutionary importance of amino acids within a protein sequence.
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For further information contact us at helpdesk@openaire.eu - Data Repository Germany Compatibility:Not yet registeredPartners:SNSB, SNSB, Botanische Staatssammlung Muenchen, Germany Botany, Biology, BiospecimenSNSB,SNSB, Botanische Staatssammlung Muenchen, Germany
re3data: r3d100011870
IndExs is a database comprising information on exsiccatae (=exsiccatal series) with titles, abbreviations, bibliography and provides a unique and persistent Exsiccata ID for each series. Exsiccatae are defined as "published, uniform, numbered sets of preserved specimens distributed with printed labels" (Pfister 1985). Please note that there are two similar latin terms: "exsiccata, ae" is feminine and used for a set of dried specimens as defined above, whereas the term "exsiccatum, i" is neutral and used for dried specimens in general. If available, images of one or more examplary labels are added to give layout information. IndExs is powered by the Diversity Workbench database framework.
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re3data: r3d100010629
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