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- Data Repository Netherlands Compatibility:Not yet registeredPartners:Erfgoed centrum Zutphen Humanities and Social Sciences, History, HumanitiesErfgoed centrum Zutphen
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Detection of functional divergence in human protein families. Cube-DB is a database of pre-evaluated conservation and specialization scores for residues in paralogous proteins belonging to multi-member families of human proteins. Protein family classification follows (largely) the classification suggested by HUGO Gene Nomenclature Committee. Sets of orthologous protein sequences were generated by mutual-best-hit strategy using full vertebrate genomes available in Ensembl. The scores, described on documentation page, are assigned to each individual residue in a protein, and presented in the form of a table (html or downloadable xls formats) and mapped, when appropriate, onto the related structure (Jmol, Pymol, Chimera).
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- Data Repository Netherlands Compatibility:Not yet registeredPartners:Erfgoed centrum Zutphen Humanities and Social Sciences, History, HumanitiesErfgoed centrum Zutphen
re3data: r3d100013336
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For further information contact us at helpdesk@openaire.eu - Data Repository Singapore Compatibility:Not yet registeredPartners:Evolution of Protein Structure and Function Group, Biomolecular Modelling and Design Division, Bioinformatics Institute, Singapore Life Science, Multiple sequence alignment, molecular_functionEvolution of Protein Structure and Function Group, Biomolecular Modelling and Design Division, Bioinformatics Institute, Singapore
Detection of functional divergence in human protein families. Cube-DB is a database of pre-evaluated conservation and specialization scores for residues in paralogous proteins belonging to multi-member families of human proteins. Protein family classification follows (largely) the classification suggested by HUGO Gene Nomenclature Committee. Sets of orthologous protein sequences were generated by mutual-best-hit strategy using full vertebrate genomes available in Ensembl. The scores, described on documentation page, are assigned to each individual residue in a protein, and presented in the form of a table (html or downloadable xls formats) and mapped, when appropriate, onto the related structure (Jmol, Pymol, Chimera).
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