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mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
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MobiDB is a database of intrinsically disordered regions (IDRs) and related features from various sources and prediction tools. Different levels of reliability and different features are reported as different and independent annotations. The database features three levels of annotation: manually curated, indirect and predicted. MobiDB annotates the binding modes of disordered proteins, whether they undergo disorder-to-order transitions or remain disordered in the bound state. In addition, disordered regions undergoing liquid-liquid phase separation or post-translational modifications are defined.
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The PR2 reference sequence database began as part of the BioMarks project from previous work in the Plankton Group of the Station Biologique of Roscoff. It aims to provide a reference database of carefully annotated 18S rRNA sequences using nine unique taxonomic fields (from domain to species). At present, it contains over 240,000 sequences. Although it focuses on protists, it also contains sequences from metazoa, fungi and plants as well a limited set of 16S sequences from plastids and bacteria. Several metadata fields are available for many sequences, including geo-localisation, whether it originates from a culture or a natural sample, and host type. The annotation of PR2 is performed by experts in each of the taxonomic groups.
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re3data: r3d100011478
PomBase is a model organism database that provides organization of and access to scientific data for the fission yeast Schizosaccharomyces pombe. PomBase supports genomic sequence and features, genome-wide datasets and manual literature curation as well as providing structural and functional annotation and access to large-scale data sets.
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The Hydra repository was a digital archive for the University of Hull. It was developed to hold, manage, preserve and provide access to the growing body of digital material generated through the research, teaching and administrative activities of the University.
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- Institutional Repository United Kingdom Compatibility:collected from a compatible aggregatorPartners:University of Cumbria MultidisciplinaryUniversity of Cumbria
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mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
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MobiDB is a database of intrinsically disordered regions (IDRs) and related features from various sources and prediction tools. Different levels of reliability and different features are reported as different and independent annotations. The database features three levels of annotation: manually curated, indirect and predicted. MobiDB annotates the binding modes of disordered proteins, whether they undergo disorder-to-order transitions or remain disordered in the bound state. In addition, disordered regions undergoing liquid-liquid phase separation or post-translational modifications are defined.
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The PR2 reference sequence database began as part of the BioMarks project from previous work in the Plankton Group of the Station Biologique of Roscoff. It aims to provide a reference database of carefully annotated 18S rRNA sequences using nine unique taxonomic fields (from domain to species). At present, it contains over 240,000 sequences. Although it focuses on protists, it also contains sequences from metazoa, fungi and plants as well a limited set of 16S sequences from plastids and bacteria. Several metadata fields are available for many sequences, including geo-localisation, whether it originates from a culture or a natural sample, and host type. The annotation of PR2 is performed by experts in each of the taxonomic groups.
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re3data: r3d100011478
PomBase is a model organism database that provides organization of and access to scientific data for the fission yeast Schizosaccharomyces pombe. PomBase supports genomic sequence and features, genome-wide datasets and manual literature curation as well as providing structural and functional annotation and access to large-scale data sets.
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For further information contact us at helpdesk@openaire.eu - Data Repository United Kingdom Compatibility:Not yet registeredPartners:University of Hull Life Science, Computer Science, PhysicsUniversity of Hull
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The Hydra repository was a digital archive for the University of Hull. It was developed to hold, manage, preserve and provide access to the growing body of digital material generated through the research, teaching and administrative activities of the University.
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