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5,554 Data sources

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  • The Therapeutic Structural Antibody Database tracks all antibody- and nanobody-related therapeutics recognized by the World Health Organisation (WHO), and identifies any corresponding structures in the Structural Antibody Database (SAbDab) with near-exact or exact variable domain sequence matches. Thera-SAbDab is synchronized with SAbDab to update weekly, reflecting new Protein Data Bank entries and the availability of new sequence data published by the WHO. Each therapeutic summary page lists structural coverage (with links to the appropriate SAbDab entries), alignments showing where any near-matches deviate in sequence, and accompanying metadata, such as intended target and investigated conditions. Thera-SAbDab can be queried by therapeutic name, by a combination of metadata, or by variable domain sequence - returning all therapeutics that are within a specified sequence identity over a specified region of the query. The sequences of all therapeutics listed in Thera-SAbDab are downloadable as a single file with accompanying metadata.

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  • OKCAM (Ontology-based Knowledgebase for Cell Adhesion Molecules) is an online resource for human genes known or predicted to be related to the processes of cell adhesion. These genes include members of the cadherin, immunoglobulin/FibronectinIII (IgFn), integrin, neurexin, neuroligin, and catenin families.

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  • The Pathway Interaction Database is a highly-structured, curated collection of information about known biomolecular interactions and key cellular processes assembled into signaling pathways.

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  • Ocean Gene Atlas(OGA) is a webservice to explore the biogeography of marine genes based on sequence similarity with environmental genomics datasets. OGA is currently implemented with the Tara Ocean Microbiome-Reference Gene Catalog database and the Marine Atlas of Tara Ocean Unigenes. Gene abundance estimates are computed for DNA metagenomes from the smallest Tara Oceans size fractions (from 0 to 3 µm, OM-RGC), and for RNA metatranscriptomes from Tara Oceans larger size fractions (0.8 to 2000µm, MATOU). OGA also includes curated Tara Oceans Eukaryotic Metagenome and Single-Cell Assembled Genomes (MAGs and SAGs), metagenomics-based transcriptomes (MGTs) and metagenome-assembled bacterial and archaeal genomes from the polar Arctic Ocean (Arctic MAG+G).

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  • MatrixDB stores experimental data established by full-length proteins, matricryptins, glycosaminoglycans, lipids and cations. MatrixDB reports interactions with individual polypeptide chains or with multimers (e.g. collagens, laminins, thrombospondins) when appropriate. Multimers are treated as permanent complexes, referencing EBI identifiers when possible. Human interactions were inferred from non-human homologous interactions when available.

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  • The European Searchable Tumour Line Database (ESTDAB) Database and Cell Bank provide a service enabling investigators to search online for HLA typed, immunologically characterised tumour cells.

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  • Explore Bristol Research provides access to the research activities of the institution. The site includes research profiles, publications, and activities. The OAI-PMH feed is limited to include only publications and theses that have associated full text files. The interface is available in English.

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  • The UK Stem Cell Bank (UKSCB) facilitates the use and sharing of quality-controlled stem cell lines to support scientific research and clinical development of stem cell therapies. The work of the UK Stem Cell Bank covers three main areas: banking for all UK-derived human embryonic stem cell lines, research in the standardisation, quality and safety of human pluripotent stem cell (hPSC)-based products, and regulation regarding international best practice, policies and guidelines relating to stem cell use and regulation around the world.

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5,554 Data sources
  • The Therapeutic Structural Antibody Database tracks all antibody- and nanobody-related therapeutics recognized by the World Health Organisation (WHO), and identifies any corresponding structures in the Structural Antibody Database (SAbDab) with near-exact or exact variable domain sequence matches. Thera-SAbDab is synchronized with SAbDab to update weekly, reflecting new Protein Data Bank entries and the availability of new sequence data published by the WHO. Each therapeutic summary page lists structural coverage (with links to the appropriate SAbDab entries), alignments showing where any near-matches deviate in sequence, and accompanying metadata, such as intended target and investigated conditions. Thera-SAbDab can be queried by therapeutic name, by a combination of metadata, or by variable domain sequence - returning all therapeutics that are within a specified sequence identity over a specified region of the query. The sequences of all therapeutics listed in Thera-SAbDab are downloadable as a single file with accompanying metadata.

    more_vert
  • more_vert
  • OKCAM (Ontology-based Knowledgebase for Cell Adhesion Molecules) is an online resource for human genes known or predicted to be related to the processes of cell adhesion. These genes include members of the cadherin, immunoglobulin/FibronectinIII (IgFn), integrin, neurexin, neuroligin, and catenin families.

    more_vert
  • The Pathway Interaction Database is a highly-structured, curated collection of information about known biomolecular interactions and key cellular processes assembled into signaling pathways.

    more_vert
  • Ocean Gene Atlas(OGA) is a webservice to explore the biogeography of marine genes based on sequence similarity with environmental genomics datasets. OGA is currently implemented with the Tara Ocean Microbiome-Reference Gene Catalog database and the Marine Atlas of Tara Ocean Unigenes. Gene abundance estimates are computed for DNA metagenomes from the smallest Tara Oceans size fractions (from 0 to 3 µm, OM-RGC), and for RNA metatranscriptomes from Tara Oceans larger size fractions (0.8 to 2000µm, MATOU). OGA also includes curated Tara Oceans Eukaryotic Metagenome and Single-Cell Assembled Genomes (MAGs and SAGs), metagenomics-based transcriptomes (MGTs) and metagenome-assembled bacterial and archaeal genomes from the polar Arctic Ocean (Arctic MAG+G).

    more_vert
  • MatrixDB stores experimental data established by full-length proteins, matricryptins, glycosaminoglycans, lipids and cations. MatrixDB reports interactions with individual polypeptide chains or with multimers (e.g. collagens, laminins, thrombospondins) when appropriate. Multimers are treated as permanent complexes, referencing EBI identifiers when possible. Human interactions were inferred from non-human homologous interactions when available.

    more_vert
  • The European Searchable Tumour Line Database (ESTDAB) Database and Cell Bank provide a service enabling investigators to search online for HLA typed, immunologically characterised tumour cells.

    more_vert
  • Explore Bristol Research provides access to the research activities of the institution. The site includes research profiles, publications, and activities. The OAI-PMH feed is limited to include only publications and theses that have associated full text files. The interface is available in English.

    more_vert
  • more_vert
  • The UK Stem Cell Bank (UKSCB) facilitates the use and sharing of quality-controlled stem cell lines to support scientific research and clinical development of stem cell therapies. The work of the UK Stem Cell Bank covers three main areas: banking for all UK-derived human embryonic stem cell lines, research in the standardisation, quality and safety of human pluripotent stem cell (hPSC)-based products, and regulation regarding international best practice, policies and guidelines relating to stem cell use and regulation around the world.

    more_vert
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