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- Data Repository China (People's Republic of) Compatibility:Not yet registeredPartners:CAFS, NSTI Life Sciences, Basic Biological and Medical Research, Cell BiologyCAFS,NSTI
re3data: r3d100013765
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re3data: r3d100013758
NODE (The National Omics Data Encyclopedia) provides an integrated, compatible, comparable, and scalable multi-omics resource platform that supports flexible data management and effective data release. NODE uses a hierarchical data architecture to support storage of muti-omics data including sequencing data, MS based proteomics data, MS or NMR based metabolomics data, and fluorescence imaging data. Launched in early 2017, NODE has collected and published over 900 terabytes of omics data for researchers from China and all over the world in last three years, 22% of which contains multiple omics data. NODE provides functions around the whole life cycle of omics data, from data archive, data requests/responses to data sharing, data analysis, data review and publish.
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mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
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For further information contact us at helpdesk@openaire.eu - Data Repository China (People's Republic of) Compatibility:Not yet registeredPartners:GMU, Sun Yat-sen Memorial Hospital Bioinformatics, Data Integration, data storageGMU,Sun Yat-sen Memorial Hospital
FerrDb V2 contains 1001 ferroptosis regulators and 143 ferroptosis-disease associations manually curated from 3288 articles. Specifically, there are 621 gene regulators, of which 264 are drivers, 238 are suppressors, 9 are markers, and 110 are unclassified genes; and there are 380 substance regulators, with 201 inducers and 179 inhibitors. Compared to FerrDb V1, curated articles increase by > 300%, ferroptosis regulators increase by 175%, and ferroptosis-disease associations increase by 50.5%. Circular RNA and pseudogene are novel regulators in FerrDb V2, and the percentage of non-coding RNA increases from 7.3% to 13.6%. External gene-related data were integrated, enabling thought-provoking and gene-oriented analysis in FerrDb V2.
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For further information contact us at helpdesk@openaire.eu - Data Repository Netherlands, United States Compatibility:Not yet registeredPartners:Netherlands Genomic Initiative, CHLA Phenomics, Biomedical Science, GenomicsNetherlands Genomic Initiative,CHLA
The Mitochondrial Disease Sequence Data Resource (MSeqDR) is a centralized genome and phenome bioinformatics resource built by the mitochondrial disease community to facilitate clinical diagnosis and research investigations of individual patient phenotypes, genomes, genes, and variants. It integrates community knowledge from expert‐curated databases with genomic and phenotype data shared by clinicians and researchers.
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For further information contact us at helpdesk@openaire.eu - Data Repository China (People's Republic of) Compatibility:Not yet registeredPartners:CAS, IOZ, MOST, 中华人民共和国财政部, 国家干细胞资源库 Life Sciences, Basic Biological and Medical Research, Cell BiologyCAS, IOZ,MOST,中华人民共和国财政部,国家干细胞资源库
re3data: r3d100013780
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For further information contact us at helpdesk@openaire.eu - Data Repository United States, Pakistan Compatibility:Not yet registeredPartners:HHSD, NLM, NIH Life Sciences, Basic Biological and Medical Research, AnatomyHHSD,NLM,NIH
re3data: r3d100010315
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For further information contact us at helpdesk@openaire.eu - Data Repository United Kingdom, Netherlands Compatibility:Not yet registeredPartners:OERC, AHRC, CLARIN, CLARIN-UK Centres Humanities and Social Sciences, Linguistics, HumanitiesOERC,AHRC,CLARIN,CLARIN-UK Centres
re3data: r3d100012522
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re3data: r3d100010582
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re3data: r3d100011260
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- Data Repository China (People's Republic of) Compatibility:Not yet registeredPartners:CAFS, NSTI Life Sciences, Basic Biological and Medical Research, Cell BiologyCAFS,NSTI
re3data: r3d100013765
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re3data: r3d100013758
NODE (The National Omics Data Encyclopedia) provides an integrated, compatible, comparable, and scalable multi-omics resource platform that supports flexible data management and effective data release. NODE uses a hierarchical data architecture to support storage of muti-omics data including sequencing data, MS based proteomics data, MS or NMR based metabolomics data, and fluorescence imaging data. Launched in early 2017, NODE has collected and published over 900 terabytes of omics data for researchers from China and all over the world in last three years, 22% of which contains multiple omics data. NODE provides functions around the whole life cycle of omics data, from data archive, data requests/responses to data sharing, data analysis, data review and publish.
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mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
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For further information contact us at helpdesk@openaire.eu - Data Repository China (People's Republic of) Compatibility:Not yet registeredPartners:GMU, Sun Yat-sen Memorial Hospital Bioinformatics, Data Integration, data storageGMU,Sun Yat-sen Memorial Hospital
FerrDb V2 contains 1001 ferroptosis regulators and 143 ferroptosis-disease associations manually curated from 3288 articles. Specifically, there are 621 gene regulators, of which 264 are drivers, 238 are suppressors, 9 are markers, and 110 are unclassified genes; and there are 380 substance regulators, with 201 inducers and 179 inhibitors. Compared to FerrDb V1, curated articles increase by > 300%, ferroptosis regulators increase by 175%, and ferroptosis-disease associations increase by 50.5%. Circular RNA and pseudogene are novel regulators in FerrDb V2, and the percentage of non-coding RNA increases from 7.3% to 13.6%. External gene-related data were integrated, enabling thought-provoking and gene-oriented analysis in FerrDb V2.
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For further information contact us at helpdesk@openaire.eu - Data Repository Netherlands, United States Compatibility:Not yet registeredPartners:Netherlands Genomic Initiative, CHLA Phenomics, Biomedical Science, GenomicsNetherlands Genomic Initiative,CHLA
The Mitochondrial Disease Sequence Data Resource (MSeqDR) is a centralized genome and phenome bioinformatics resource built by the mitochondrial disease community to facilitate clinical diagnosis and research investigations of individual patient phenotypes, genomes, genes, and variants. It integrates community knowledge from expert‐curated databases with genomic and phenotype data shared by clinicians and researchers.
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For further information contact us at helpdesk@openaire.eu - Data Repository China (People's Republic of) Compatibility:Not yet registeredPartners:CAS, IOZ, MOST, 中华人民共和国财政部, 国家干细胞资源库 Life Sciences, Basic Biological and Medical Research, Cell BiologyCAS, IOZ,MOST,中华人民共和国财政部,国家干细胞资源库
re3data: r3d100013780
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For further information contact us at helpdesk@openaire.eu - Data Repository United States, Pakistan Compatibility:Not yet registeredPartners:HHSD, NLM, NIH Life Sciences, Basic Biological and Medical Research, AnatomyHHSD,NLM,NIH
re3data: r3d100010315
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re3data: r3d100012522
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re3data: r3d100010582
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re3data: r3d100011260
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