Research careers are often shaped early and can be difficult to redirect later, with many early-stage researchers (R1 and R2) in the EU facing challenges in navigating diverse career paths. Fragmented transitions between academia, industry, the public sector, and entrepreneurial ventures—along with the absence of cohesive frameworks—have hindered career mobility, skill development, and employability, particularly in fast-growing fields such as AI, digital transformation, and deep tech. NextTechTalents addresses these challenges by creating talent ecosystems that integrate these sectors, ensuring researchers gain the skills to transition between academia and non-academic environments, including entrepreneurial opportunities. By supporting researchers in building various skills, the project helps them commercialise innovations and pursue different ventures, contributing to a sustainable talent pool across the European Research Area. NextTechTalents, aligned with the goals of the European Research Area, aims to create a robust and sustainable talent ecosystem, fostering talent circulation across sectors and enhancing employability and mobility. The project develops tailored career services, mentoring programs, and training modules based on the ResearchComp framework to equip researchers with the tools for both academic and non-academic pathways. NextTechTalents, will create a comprehensive Handbook for HR managers and training providers within research and innovation organizations. This handbook will guide the integration of the NextTechTalents Training System, promote interdisciplinary skills acquisition, and strengthen collaboration across academia, industry, and entrepreneurial ventures. By addressing mobility, cross-sector employability, and inclusive career support, the project will help early-stage researchers thrive in evolving, competitive sectors.