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University of Pisa
Country: Italy
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421 Projects, page 1 of 85
  • Funder: EC Project Code: 101061427
    Funder Contribution: 172,750 EUR

    MobiliTy investigates Middle and early Upper Palaeolithic human organisation to exploit the landscape resources in NW Tuscany. Hunter-gatherers’ (HGs) mobility patterns are understood to be in a spectrum between residential and logistical mobility. HGs have shown to have site-furniture, personal and situational gear, with different levels of manufacture and maintenance curation. Around 40 ka cal BP a technological and human species’ shift occurred in Europe, referred as the Middle-Upper Palaeolithic Transition. The northern Tyrrhenian region is one of the few European areas that yielded a cluster of last Neanderthal sites and the presence of early H. sapiens. It is a required passage between southern France and the rest of the Italian Peninsula, and the further investigation of this area could shed light on the colonisation process of H. sapiens and its relationship with the demise of H. neanderthalensis. The sites in NW Tuscany are showing a different raw material provisioning, in particular early H. sapiens introduced the exotic Scaglia Marchigiana chert, showing a long-extended network that spans from NW Italy until the central eastern Apennines. The action is an interdisciplinary endeavour to better understand differences of land-use patterns and reconstructing mobility patterns in the NW Tuscany across the Middle-Upper Transition period, through the technological analysis of the artefacts and the definition of raw material circulation.

  • Funder: EC Project Code: 101030496
    Overall Budget: 183,473 EURFunder Contribution: 183,473 EUR

    The main objectives of VALIDATIO are to first characterize the chemical reactions of Lead-Lithium, water, and non-condensable gases, under conditions similar to those expected for the European water cooled lead lithium (WCLL) breeding blanket (BB) under accident conditions and the creation of an experimental database for SIMMER code validation by performing series of experiments at the existing experimental facility LIFUS5/Mod3 (Brasimone, Italy) (this part of the work is very challenging since reaction characteristics of Lead-Lithium, water and non-condensable is highly sensitive to thermo-dynamic conditions of the environment (pressure, temperature, velocity etc.)) and based on obtained experimental data perform the verification and validation of SIMMER code, modification in code for irregularities found in the validation process and perform the safety analysis of WCLL-BB.The problem is very challenging since the available experimental data for code validation is extremely limited. Only very little useful information is available in the literature; therefore, a dedicated experimental campaign is always highly advantageous for code validation and verification under the accident scenario. This issue is also complicated since the interaction of fluids results in multi-component, multi-phase flow, which is very hard to model. I intend to perform a series of experiments on Lead-Lithium, water, and non-condensable chemical interaction (which I will design to accommodate for all the possible sample conditions that may encounter under WCLL-BB under different accident conditions) at the experimental facility, LIFUS5/Mod3 to obtain the database and to experimentally characterize the process. The obtained database will be utilized for the validation, verification, and modification of the SIMMER code to improve the numerical modeling capability of the code to simulate such accident scenarios.

  • Funder: EC Project Code: 801715
    Overall Budget: 1,490,380 EURFunder Contribution: 1,490,380 EUR

    Vision is probably the best understood system of the human brain: studying vision has taught us much about the human mind and its complex processes. We know in detail the fundamental steps leading to visual perception, but we do not know why normally sighted people differ in how they perceive: why some “see the forest before the trees”, while others have a fragmented perceptual experience focused on local features. PUPILTRAITS aims to fill this gap by taking an innovative approach to vision science, to understand how vision is affected by physiological state and personality traits. I will measure visual processing with both classic and new methods (that I helped develop), including pupil responses, ultra-high field Magnetic Resonance of human visual cortex, and psychophysics. Based on solid pilot data, I predict that differences in behavioral and cortical properties co-vary with personality traits, providing new reliable biomarkers of the local context-independent perception associated with autistics traits, even in young children (using pupillometry). These tools will also reveal changes of perception within individuals: during a safe and simple physiological intervention (ketosis, a metabolic state that can be naturally induced by fasting and intense physical activity), to show that early visual processing can be altered by acting on metabolism, and that this consequently affects holistic/local perceptual styles. My aim is to provide new knowledge on the relationship between metabolism, cortical processing and perception. This has the potential for a strong societal impact: it can change our understanding of pervasive developmental disorders, like Autistic Spectrum Disorders, characterized by a different way of processing incoming information; it can aid their diagnosis through objective evaluation of perceptual styles, and encourage innovative therapeutic approaches aimed at changing perception and behavior by acting on general physiology: how we eat and exercise

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  • Funder: EC Project Code: 235016
  • Funder: NIH Project Code: 5U01MH033922-06

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