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87 research outcomes, page 1 of 9
  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Carlos Ruiz-Arenas; Carles Hernandez-Ferrer; Marta Vives-Usano; Sergi Mari; Inés Quintela; Dan Mason; Solène Cadiou; Maribel Casas; Sandra Andrusaityte; Kristine B. Gutzkow; ...
    Publisher: eLife Sciences Publications
    Country: Spain
    Project: EC | ESCAPE (211250), WT , EC | CHICOS (241604), EC | ATHLETE (874583), EC | ENVIROGENOMARKERS (226756), EC | LIFECYCLE (733206), EC | HELIX (308333), EC | ENRIECO (226285)

    Background:The identification of expression quantitative trait methylation (eQTMs), defined as associations between DNA methylation levels and gene expression, might help the biological interpretation of epigenome-wide association studies (EWAS). We aimed to identify au...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Hayes, A.; Nguyen, D.; Andersson, M.; Antó n, A.; Bailly, J.; Beard, S.; Benschop, K.S.M.; Berginc, N.; Blomqvist, S.; ...
    Publisher: HAL CCSD
    Countries: Spain, Norway, Netherlands, Italy, Finland, France
    Project: EC | BIORISE (669026), EC | OrganoVIR (812673), WT , WT | Institutional Strategic S... (204826), EC | COMPARE (643476)

    Polymerase chain reaction (PCR) detection has become the gold standard for diagnosis and typing of enterovirus (EV) and human parechovirus (HPeV) infections. Its effectiveness depends critically on using the appropriate sample types and high assay sensitivity as viral l...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Barbara Mühlemann; Lasse Vinner; Ashot Margaryan; Helene Wilhelmson; Constanza de la Fuente Castro; Morten E. Allentoft; Peter de Barros Damgaard; Anders J. Hansen; Sofie Holtsmark Nielsen; Lisa Strand; ...
    Countries: Norway, Denmark, Netherlands, Denmark
    Project: WT , EC | COMPARE (643476)

    Humans have a notable capacity to withstand the ravages of infectious diseases. Smallpox killed millions of people but drove Jenner's invention of vaccination, which eventually led to the annihilation of this virus, declared in 1980. To investigate the history of smallp...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Muloi, Dishon; Fevre, Eric M; Bettridge, Judy; Rono, Robert; Ong'are, Daniel; Hassell, James M; Karani, Maurice K; Muinde, Patrick; van Bunnik, Bram; Street, Alice; ...
    Publisher: Edinburgh University Global Health Society
    Country: United Kingdom
    Project: WT | How do bacteria and their... (103953), EC | COMPARE (643476)

    Background: Antimicrobial resistance (AMR) driven by antibiotic consumption is a growing global health threat. However, data on antimicrobial consumption patterns in low- and middle-income countries (LMICs) is sparse. Here, we investigate the patterns of antibiotic sale...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Amid, Clara; Alako, Blaise T F; Balavenkataraman Kadhirvelu, Vishnukumar; Burdett, Tony; Burgin, Josephine; Fan, Jun; Harrison, Peter W; Holt, Sam; Hussein, Abdulrahman; Ivanov, Eugene; ...
    Persistent Identifiers
    Publisher: Oxford University Press
    Project: EC | AQUA-FAANG (817923), EC | COMPARE (643476), WT , EC | EMBRIC (654008), EC | RECODID (825746), EC | EASI-Genomics (824110), EC | ENVRI PLUS (654182), EC | GENE-SWitCH (817998), EC | ELIXIR-EXCELERATE (676559), EC | ZIKAlliance (734548)

    Abstract The European Nucleotide Archive (ENA, https://www.ebi.ac.uk/ena) at the European Molecular Biology Laboratory’s European Bioinformatics Institute provides open and freely available data deposition and access services across the spectrum of nucleotide sequence d...

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  • publication . Article . Preprint . 2019
    Open Access English
    Authors:
    Pataki B.A.; Matamoros S.; van der Putten B.C.L.; Remondini D.; Giampieri E.; Aytan-Aktug D.; Hendriksen R.S.; Lund O.; Csabai I.; Schultsz C.; ...
    Publisher: Cold Spring Harbor Laboratory
    Countries: Denmark, Italy
    Project: WT , EC | COMPARE (643476)

    2.AbstractA possible way to tackle the crisis of antimicrobial resistance development is a strict policy when prescribing antibiotics. Thus, it is important that prescriptions are based on antimicrobial susceptibility data to ensure effective treatment outcomes. The inc...

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  • publication . Preprint . 2019
    Open Access
    Authors:
    Lu, Lu; Brierley, Liam; Robertson, Gail; Zhang, Feifei; Lycett, Samantha; Smith, Donald; Chase-Topping, Margo; Simmonds, Peter; Woolhouse, Mark;
    Persistent Identifiers
    Publisher: bioRxiv
    Project: WT | Wellcome Trust-Vietnam in... (093724), UKRI | Pathogen diversity, host ... (BBS/E/D/20002173), EC | COMPARE (643476)

    AbstractTo have epidemic potential, a pathogen must be able to spread in human populations, but of human-infective RNA viruses only a minority can do so. We investigated the evolution of human transmissibility through parallel analyses of 1755 virus genome sequences fro...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Hendriksen, Rene S.; Bortolaia, Valeria; Tate, Heather; Tyson, Gregory H.; Aarestrup, Frank M.; McDermott, Patrick F.;
    Persistent Identifiers
    Publisher: Frontiers Media S.A.
    Country: Denmark
    Project: WT , EC | COMPARE (643476)

    The recent advancements in rapid and affordable DNA sequencing technologies have revolutionized diagnostic microbiology and microbial surveillance. The availability of bioinformatics tools and online accessible databases has been a prerequisite for this. We conducted a ...

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  • publication . Article . Preprint . 2019
    Open Access
    Authors:
    Danielle J. Ingle; Satheesh Nair; Hassan Hartman; Philip M. Ashton; Zoe A. Dyson; Martin Day; Joanne Freedman; Marie Anne Chattaway; Kathryn E. Holt; Timothy J. Dallman;
    Publisher: Public Library of Science (PLoS)
    Country: United Kingdom
    Project: WT | A strategic vision to dri... (106158), EC | COMPARE (643476), NHMRC | A new genomic frontier fo... (1129770)

    Salmonella enterica serovar Typhi (S. Typhi) is the causative agent of typhoid fever, a systemic human infection with a burden exceeding 20 million cases each year that occurs disproportionately among children in low and middle income countries. Antimicrobial therapy is...

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  • publication . Preprint . 2019
    Open Access
    Authors:
    Frentrup, Martinique; Zhou, Zhemin; Steglich, Matthias; Meier-Kolthoff, Jan P.; Göker, Markus; Riedel, Thomas; Bunk, Boyke; Spröer, Cathrin; Overmann, Jörg; Blaschitz, Marion; ...
    Persistent Identifiers
    Publisher: bioRxiv
    Project: WT | Wellcome Trust Sanger Ins... (098051), UKRI | EnteroBase: A Powerful, U... (BB/L020319/1), WT | Deep evolutionary history... (202792), EC | COMPARE (643476)

    AbstractClostridioides difficile is the primary infectious cause of antibiotic-associated diarrhea. Local transmissions and international outbreaks of this pathogen have been previously elucidated by bacterial whole-genome sequencing, but comparative genomic analyses at...

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87 research outcomes, page 1 of 9