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description Publicationkeyboard_double_arrow_right Article , Other literature type 2015 Spain, Switzerland, Australia, NetherlandsPublisher:Environmental Health Perspectives Funded by:EC | ESCAPEEC| ESCAPESchembari, Anna; de Hoogh, Kees; Pedersen, Marie; Dadvand, Payam; Martinez, David; Hoek, Gerard; Petherick, Emily S; Wright, John; Nieuwenhuijsen, Mark J; LS IRAS EEPI ME (Milieu epidemiologie); Risk Assessment of Toxic and Immunomodulatory Agents; IRAS RATIA2;BACKGROUND: Exposure to ambient air pollution has been associated with reduced size of newborns; however, the modifying effect of maternal ethnicity remains little explored among South Asians. OBJECTIVES: We investigated ethnic differences in the association between ambient air pollution and newborn's size. METHOD: Pregnant women were recruited between 2007 and 2010 for the Born in Bradford cohort study, in England. Exposures to particulate matter (≤ 10 μm, PM10; ≤ 2.5 μm, PM2.5), PM2.5 absorbance, and nitrogen oxides (NOx, NO2) were estimated using land-use regressions models. Using multivariate linear regression models, we evaluated effect modification by maternal ethnicity ("white British" or "Pakistani origin," self-reported) on the associations of air pollution and birth weight, head circumference, and triceps and subscapular skinfold thickness. RESULTS: A 5-μg/m3 increase in mean third trimester PM2.5 was associated with significantly lower birth weight and smaller head circumference in children of white British mothers (-43 g; 95% CI: -76, -10 and -0.28 cm; 95% CI: -0.39, -0.17, respectively), but not in children of Pakistani origin (9 g; 95% CI: -17, 35 and -0.08 cm; 95% CI: -0.17, 0.01, respectively) (p(int) = 0.03 and < 0.001). In contrast, PM2.5 was associated with significantly larger triceps and subscapular skinfold thicknesses in children of Pakistani origin (0.17 mm; 95% CI: 0.08, 0.25 and 0.21 mm; 95% CI: 0.12, 0.29, respectively), but not in white British children (-0.02 mm; 95% CI: -0.14, 0.01 and 0.06 mm; 95% CI: -0.06, 0.18, respectively) (p(int) = 0.06 and 0.11). Patterns of associations for PM10 and PM2.5 absorbance according to ethnicity were similar to those for PM2.5, but associations of the outcomes with NO2 and NOx were mostly nonsignificant in both ethnic groups. CONCLUSIONS: Our results suggest that associations of ambient PM exposures with newborn size and adiposity differ between white British and Pakistani origin infants. This project was jointly supported by the ESCAPE (European Study of Cohorts for Air Pollution Effects) project funded under the European Union’s Seventh Framework Programme (grant agreement number 211250), and the National Institute for Health Research (NIHR) under its Collaboration for Applied Health Research and Care (CLAHRC) Yorkshire and Humberside Programme. A.S. holds a predoctoral fellowship awarded from the Spanish Ministry of Economy and Finance, Instituto de Salud Carlos III-FEDER fellowship (PFIS grant FI 10/00476); M.P. holds a “Juan de la Cierva” postdoctoral fellowship awarded by the Spanish Ministry of Science and Innovation (JCI-2011-09937). P.D. holds a “Ramón y Cajal” fellowship (RYC-2012-10995) awarded by the Spanish Ministry of Economy and Competitiveness.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4629735Data sources: PubMed CentralNARCIS; Utrecht University RepositoryArticle . 2015Environmental Health Perspectives; UPF Digital RepositoryArticle . 2015 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 76 citations 76 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4629735Data sources: PubMed CentralNARCIS; Utrecht University RepositoryArticle . 2015Environmental Health Perspectives; UPF Digital RepositoryArticle . 2015 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Article , Other literature type 2015 Spain, Switzerland, Australia, NetherlandsPublisher:Environmental Health Perspectives Funded by:EC | ESCAPEEC| ESCAPESchembari, Anna; de Hoogh, Kees; Pedersen, Marie; Dadvand, Payam; Martinez, David; Hoek, Gerard; Petherick, Emily S; Wright, John; Nieuwenhuijsen, Mark J; LS IRAS EEPI ME (Milieu epidemiologie); Risk Assessment of Toxic and Immunomodulatory Agents; IRAS RATIA2;BACKGROUND: Exposure to ambient air pollution has been associated with reduced size of newborns; however, the modifying effect of maternal ethnicity remains little explored among South Asians. OBJECTIVES: We investigated ethnic differences in the association between ambient air pollution and newborn's size. METHOD: Pregnant women were recruited between 2007 and 2010 for the Born in Bradford cohort study, in England. Exposures to particulate matter (≤ 10 μm, PM10; ≤ 2.5 μm, PM2.5), PM2.5 absorbance, and nitrogen oxides (NOx, NO2) were estimated using land-use regressions models. Using multivariate linear regression models, we evaluated effect modification by maternal ethnicity ("white British" or "Pakistani origin," self-reported) on the associations of air pollution and birth weight, head circumference, and triceps and subscapular skinfold thickness. RESULTS: A 5-μg/m3 increase in mean third trimester PM2.5 was associated with significantly lower birth weight and smaller head circumference in children of white British mothers (-43 g; 95% CI: -76, -10 and -0.28 cm; 95% CI: -0.39, -0.17, respectively), but not in children of Pakistani origin (9 g; 95% CI: -17, 35 and -0.08 cm; 95% CI: -0.17, 0.01, respectively) (p(int) = 0.03 and < 0.001). In contrast, PM2.5 was associated with significantly larger triceps and subscapular skinfold thicknesses in children of Pakistani origin (0.17 mm; 95% CI: 0.08, 0.25 and 0.21 mm; 95% CI: 0.12, 0.29, respectively), but not in white British children (-0.02 mm; 95% CI: -0.14, 0.01 and 0.06 mm; 95% CI: -0.06, 0.18, respectively) (p(int) = 0.06 and 0.11). Patterns of associations for PM10 and PM2.5 absorbance according to ethnicity were similar to those for PM2.5, but associations of the outcomes with NO2 and NOx were mostly nonsignificant in both ethnic groups. CONCLUSIONS: Our results suggest that associations of ambient PM exposures with newborn size and adiposity differ between white British and Pakistani origin infants. This project was jointly supported by the ESCAPE (European Study of Cohorts for Air Pollution Effects) project funded under the European Union’s Seventh Framework Programme (grant agreement number 211250), and the National Institute for Health Research (NIHR) under its Collaboration for Applied Health Research and Care (CLAHRC) Yorkshire and Humberside Programme. A.S. holds a predoctoral fellowship awarded from the Spanish Ministry of Economy and Finance, Instituto de Salud Carlos III-FEDER fellowship (PFIS grant FI 10/00476); M.P. holds a “Juan de la Cierva” postdoctoral fellowship awarded by the Spanish Ministry of Science and Innovation (JCI-2011-09937). P.D. holds a “Ramón y Cajal” fellowship (RYC-2012-10995) awarded by the Spanish Ministry of Economy and Competitiveness.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4629735Data sources: PubMed CentralNARCIS; Utrecht University RepositoryArticle . 2015Environmental Health Perspectives; UPF Digital RepositoryArticle . 2015 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1289/ehp.1408675&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 76 citations 76 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4629735Data sources: PubMed CentralNARCIS; Utrecht University RepositoryArticle . 2015Environmental Health Perspectives; UPF Digital RepositoryArticle . 2015 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1289/ehp.1408675&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu