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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Quartinello, Felice; Vajnhandl, Simona; Volmajer Valh, Julija; Farmer, Thomas; +5 Authors

    therefore, achieving a complete poly(ethylene terephthalate) (PET) hydrolysis in an environmentally friendly way is a current challenge. In this work, a chemo-enzymatic treatment was developed to recover the PET building blocks, namely terephthalic acid (TA) and ethylene glycol. To monitor the monomer and oligomer content in solid samples, a Fourier-transformed Raman method was successfully developed. A shift of the free carboxylic groups (1632 cm$^{−1}$) of TA into the deprotonated state (1604 and 1398 cm$^{−1}$) was observed and bands at 1728 and 1398 cm$^{−1}$ were used to assess purity of TA after the chemo-enzymatic PET hydrolysis. The chemical treatment, performed under neutral conditions (T = 250 °C, P = 40 bar), led to conversion of PET into 85% TA and small oligomers. The latter were hydrolysed in a second step using the Humicola insolens cutinase (HiC) yielding 97% pure TA, therefore comparable with the commercial synthesis-grade TA (98%). Due to the rising global environment protection awareness, recycling strategies that comply with the circular economy principles are needed. Polyesters are among the most used materials in the textile industry

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Digital library of U...arrow_drop_down
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Vremec, Matevž;

    The groundwater pumping station at Vrbanski plato is the most substantial water source of the Maribor water system. The aquifer is recharged from the river Drava and is conseguently independent of droughts and climate changes, therefore it is significant for the undisturbed supply of drinking water to the residents of Maribor. The importance of the groundwater pumping station demands highly effective management, for which it is crucial to design a valid mathematical groundwater flow model. The present diploma thesis covers the groundwater flow modelling in the area of the aquifer Vrbanski plato. The data used for the development, calibration and simulation of the model was obtained from the archives of the company IEI – Ecological engineering institute d.o.o., and from other literature. Črpališče Vrbanski plato je najizdatnejši vodni vir Mariborskega vodovoda. Napaja se iz reke Drave in je tako neodvisen od sušnih obdobij in klimatskih sprememb, kar je ključnega pomena za nemoteno oskrbo prebivalstva s pitno vodo. Pomembnost črpališča zato zahteva učinkovito upravljanje, za katerega je potreben kvaliteten hidrogeološki informacijski sistem, ki je zasnovan na podlagi simulacij matematičnega modela toka podzemne vode. Diplomsko delo tako obravnava modeliranje podzemne vode na območju vodonosnika Vrbanski plato. Za izdelavo, kalibracijo ter simulacijo modela so bili uporabljeni podatki iz arhivov podjetja IEI (Inštitut za ekološki inženiring d.o.o.) ter druge literature.

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    Authors: Batorek Lukač, Nina; Kress, Kevin; Čandek-Potokar, Marjeta; Fazarinc, Gregor; +5 Authors

    average age = 186 days) as positive and negative controls, respectively. Objectives: We hypothesized that the timing of gonadotropin-releasing hormone suppression (early or late sexual development phases) influences the extent of reproductive function inhibition, histological structure of testicular tissue, and expression levels of selected genes related to steroid metabolism. Materials and methods: Antibody titer, hormonal status, and histomorphometric analysis of testicular tissue were subjected to principal component analysis followed by hierarchical clustering to evaluate the immunocastration effectiveness in mature boars. Results: Hierarchical clustering differentiated mature immunocastrated boars clustered with young immunocastrated pigs from those clustered with entire males. Although all mature immunocastrated boars responded to vaccination, as evidenced by the increased gonadotropin-releasing hormone antibody titers (p < 0.001), decreased serum luteinizing hormone concentrations (p = 0.002), and changes in testicular tissue vascularization (lighter and less red testicular parenchyma p ≤ 0.001), the responses were variable. Sharp decreases in testes index (p < 0.001), Leydig cell volume density (p < 0.001), Leydig cell nucleus-to-cytoplasm ratio (p < 0.001), and testosterone concentration (p < 0.001) were observed in mature immunocastrated boars clustered with young immunocastrated pigs compared with those that clustered with entire males. Additionally, mature immunocastrated boars clustered with young immunocastrated pigs showed lower hydroxysteroid 17-beta dehydrogenase 7 expression than entire males (p < 0.05). The young immunocastrated pigs group showed higher folliclestimulating hormone receptors than the entire males and mature immunocastrated boars, lower steroidogenic acute regulatory protein expression levels compared with entire males, and mature immunocastrated boars clustered with entire males (p < 0.01). Conclusion: The two-dose vaccination regime resulted in progressive but variable regression of testicular function in adult (post-pubertal) pigs Background: While immunocastration has been studied in male pre-pubertal pigs, data on older, sexually mature animals are limited. To understand the physiological effects of androgen deprivation in the late sexual development phase, we compared mature immunocastrated boars (n = 19 however, it was insufficient to induce a complete immunocastration response in all animals. average age = 480 days) to young male immunocastrated pigs (n = 6 average age = 183 days) and young entire males (n = 6

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Digital library of U...arrow_drop_down
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Quartinello, Felice; Vajnhandl, Simona; Volmajer Valh, Julija; Farmer, Thomas; +5 Authors

    therefore, achieving a complete poly(ethylene terephthalate) (PET) hydrolysis in an environmentally friendly way is a current challenge. In this work, a chemo-enzymatic treatment was developed to recover the PET building blocks, namely terephthalic acid (TA) and ethylene glycol. To monitor the monomer and oligomer content in solid samples, a Fourier-transformed Raman method was successfully developed. A shift of the free carboxylic groups (1632 cm$^{−1}$) of TA into the deprotonated state (1604 and 1398 cm$^{−1}$) was observed and bands at 1728 and 1398 cm$^{−1}$ were used to assess purity of TA after the chemo-enzymatic PET hydrolysis. The chemical treatment, performed under neutral conditions (T = 250 °C, P = 40 bar), led to conversion of PET into 85% TA and small oligomers. The latter were hydrolysed in a second step using the Humicola insolens cutinase (HiC) yielding 97% pure TA, therefore comparable with the commercial synthesis-grade TA (98%). Due to the rising global environment protection awareness, recycling strategies that comply with the circular economy principles are needed. Polyesters are among the most used materials in the textile industry

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Digital library of U...arrow_drop_down
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    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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    Authors: Vremec, Matevž;

    The groundwater pumping station at Vrbanski plato is the most substantial water source of the Maribor water system. The aquifer is recharged from the river Drava and is conseguently independent of droughts and climate changes, therefore it is significant for the undisturbed supply of drinking water to the residents of Maribor. The importance of the groundwater pumping station demands highly effective management, for which it is crucial to design a valid mathematical groundwater flow model. The present diploma thesis covers the groundwater flow modelling in the area of the aquifer Vrbanski plato. The data used for the development, calibration and simulation of the model was obtained from the archives of the company IEI – Ecological engineering institute d.o.o., and from other literature. Črpališče Vrbanski plato je najizdatnejši vodni vir Mariborskega vodovoda. Napaja se iz reke Drave in je tako neodvisen od sušnih obdobij in klimatskih sprememb, kar je ključnega pomena za nemoteno oskrbo prebivalstva s pitno vodo. Pomembnost črpališča zato zahteva učinkovito upravljanje, za katerega je potreben kvaliteten hidrogeološki informacijski sistem, ki je zasnovan na podlagi simulacij matematičnega modela toka podzemne vode. Diplomsko delo tako obravnava modeliranje podzemne vode na območju vodonosnika Vrbanski plato. Za izdelavo, kalibracijo ter simulacijo modela so bili uporabljeni podatki iz arhivov podjetja IEI (Inštitut za ekološki inženiring d.o.o.) ter druge literature.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Digital library of U...arrow_drop_down
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    Authors: Batorek Lukač, Nina; Kress, Kevin; Čandek-Potokar, Marjeta; Fazarinc, Gregor; +5 Authors

    average age = 186 days) as positive and negative controls, respectively. Objectives: We hypothesized that the timing of gonadotropin-releasing hormone suppression (early or late sexual development phases) influences the extent of reproductive function inhibition, histological structure of testicular tissue, and expression levels of selected genes related to steroid metabolism. Materials and methods: Antibody titer, hormonal status, and histomorphometric analysis of testicular tissue were subjected to principal component analysis followed by hierarchical clustering to evaluate the immunocastration effectiveness in mature boars. Results: Hierarchical clustering differentiated mature immunocastrated boars clustered with young immunocastrated pigs from those clustered with entire males. Although all mature immunocastrated boars responded to vaccination, as evidenced by the increased gonadotropin-releasing hormone antibody titers (p < 0.001), decreased serum luteinizing hormone concentrations (p = 0.002), and changes in testicular tissue vascularization (lighter and less red testicular parenchyma p ≤ 0.001), the responses were variable. Sharp decreases in testes index (p < 0.001), Leydig cell volume density (p < 0.001), Leydig cell nucleus-to-cytoplasm ratio (p < 0.001), and testosterone concentration (p < 0.001) were observed in mature immunocastrated boars clustered with young immunocastrated pigs compared with those that clustered with entire males. Additionally, mature immunocastrated boars clustered with young immunocastrated pigs showed lower hydroxysteroid 17-beta dehydrogenase 7 expression than entire males (p < 0.05). The young immunocastrated pigs group showed higher folliclestimulating hormone receptors than the entire males and mature immunocastrated boars, lower steroidogenic acute regulatory protein expression levels compared with entire males, and mature immunocastrated boars clustered with entire males (p < 0.01). Conclusion: The two-dose vaccination regime resulted in progressive but variable regression of testicular function in adult (post-pubertal) pigs Background: While immunocastration has been studied in male pre-pubertal pigs, data on older, sexually mature animals are limited. To understand the physiological effects of androgen deprivation in the late sexual development phase, we compared mature immunocastrated boars (n = 19 however, it was insufficient to induce a complete immunocastration response in all animals. average age = 480 days) to young male immunocastrated pigs (n = 6 average age = 183 days) and young entire males (n = 6

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Digital library of U...arrow_drop_down
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